A fatality involving cyamemazine, a phenothiazine derivative, is presented. Cyamemazine was formally identified in postmortem blood using an HPLC-DAD screening procedure, and then quantified in some postmortem samples by means of a specific HPLC method. The blood concentration of cyamemazine was 9.8 micrograms/mL. Tissue distribution of cyamemazine is discussed in light of the existing literature.

Abstract This article describes two of the most common natural sources red anthraquinones that have been used since antiquity for textile dyeing and as lake pigments, namely cochineal insect roots Rubia Relbunium plants. Carminic acid is main component carmine, colorant obtained from cochineal. Alizarin purpurin are found in extracts roots, but contain only purpurin. These identified a variety ...

ABSTRACT: This research assessed the phenolic composition of Jussara pulp from Brazilian states Minas Gerais (MG) and Espírito Santo (ES) using HPLC-DAD-MS/MS. Seventeen anthocyanins were detected in fruits, derived cyanidin, pelargonidin peonidin. Among non-anthocyanic compounds, flavonols (kaempferol, quercetin isorhamnetin derivatives), flavan-3-ols (catechin, epicatechin, B-type procyanidin...

A novel fast high-performance liquid chromatography (HPLC) method coupled with diode array detection (DAD) and time-of-flight mass spectrometry (TOF/MS) was developed for qualitative and quantitative analysis of Radix Astragali products. The potential of fast HPLC on 1.8-microm particles was compared with the performance of HPLC on conventional 5-microm particles columns. Significant advantages...

Flavonoid fraction composition of Larix dahurica Turcz. knotwood was studied with HPLC-DAD/ESI-MS/MS. Dihydroquercetin, aromadendrin, dihydroisorhamnetin, eriodictyol and quercetin were revealed as its components.

Apteranthes europaea (Guss.) Murb. subsp. maroccana (Hook.f.) Plowes (A. europaea) is a medicinal plant widely used in traditional medicines to treat various diseases including hepatic pathogenesis. This study was conducted evaluate the protective effect of chemically characterized polyphenol-rich fraction from A. on carbon tetrachloride-induced liver injury mice. The chemical characterization ...

BACKGROUND The processed roots of Polygonum multiflorum Thunb. (Heshouwu; processed HSW) are commonly used in anti-aging medicine. Few reports have combined chemical profiles with bioactivity to evaluate the quality of the processed HSW. This study aims to integrate chemometric fingerprints of antioxidant activities and high-performance liquid chromatography-diode array detection-chemiluminesce...

BACKGROUND Siwu decoction categorized formulae (SWDCF) are widely used for treating gynecological diseases. This study aims to elucidate the differences of bioactive constituents in SWDCF by ultra-high performance liquid chromatography coupled with time-of-flight mass spectrometry (UPLC - QTOF - MS /MS) and HPLC-DAD. METHODS An efficient method based on UPLC - QTOF - MS /MS was developed for ...