Homologous recombination has been a focus of basic research for over a hundred years [1–3]. The advent of genomics has allowed fine-scale analyses of recombination, including genomewide analysis of global recombination rate [4–6] and hotspot usage (the proportion of recombination that occurs at hotspots) [4,6]. Recently, PLOS Genetics published the work of Ma et al. [7] describing a genome-wide...

The heptamer sequence ATGACGT is essential for activity of the M26 meiotic recombination hotspot in the ade6 gene of Schizosaccharomyces pombe. Hotspot activity is associated with binding of the heterodimeric transcription factor Atf1.Pcr1 to M26. We have found that the sequences (C/T/G) TGACGT also bound Atf1.Pcr1 and acted as meiotic hotspots, but unlike M26 they must be followed by A or C fo...

The growing popularity of Free and Open Source (FOSS) GIS software is -without doubtsdue to the possibility to build and customize geospatial applications to meet specific requirements for any users. From this point of view, QGIS is one of the most flexible as well as fashionable GIS software environment which enables users to develop powerful geospatial applications using Python. Exploiting th...

Triana is an Earth remote sensing satellite to be located at the distant Langrange Point L-1, the gravity-neutral point between the Earth and the Sun. It will provide continuous full disk images ofthe entire sunlit side of the Earth with 8 km pixel resolution. The primary remote sensing instrument on Triana is a calibrated multispectral iniager with 10 spectral channels in the UV, VIS, and MR b...

Memory analysis is slowly moving up the software stack. Early analysis efforts focused on core OS structures and services. As this field evolves, more information becomes accessible because analysis tools can build on foundational frameworks like Volatility and Rekall. This paper demonstrates and establishes memory analysis techniques for managed runtimes, namely the HotSpot Java Virtual Machin...

Introduction: This study aimed to determine the hotspot areas for Cutaneous Leishmaniasis (CL) in Fasa city and assess the relations between the geographical factors with CL incidence using spatial analysis. Materials and Methods: This ecological study was conducted in Fasa city, data of the CL disease such as the total number of CL cases and the population at risk from 2009 to 2014. Weather c...