Relations among hormone serum concentrations are complex and depend on various factors, including gender, age, body mass index, diurnal rhythms and secretion stochastics. Therefore, endocrine deviations from healthy homeostasis are not easily detected or understood. A generic method is presented for detecting regulatory relations between hormones. This is demonstrated with a cohort of obese wom...

Hormones transported to the liver by the portal and systemic circulation regulate many hepatic functions. The mechanisms by which these hormones regulate gene expression and protein functions have been under intensive investigation in recent years. It is clear that hepatic metabolic responses to steroid and peptide hormones are generally similar to those for other hormone-sensitive tissues. Thu...