We generalize the correlation functions of the Clauser-Horne-Shimony-Holt (CHSH) inequality to arbitrarily high-dimensional systems. Based on this generalization, we construct the general CHSH inequality for bipartite quantum systems of arbitrarily high dimensionality, which takes the same simple form as CHSH inequality for two dimensions. This inequality is optimal in the same sense as the CHS...

We show that the no-disturbance principle imposes a tradeoff between locally contextual correlations violating the Klyachko-Can-Biniciogˇlu-Shumovski inequality and spatially separated correlations violating the Clauser-Horne-Shimony-Holt inequality. The violation of one inequality forbids the violation of the other. We also obtain the corresponding monogamy relation imposed by quantum theory f...

Photonic systems based on energy-time entanglement have been proposed to test local realism using the Bell inequality. A violation of this inequality normally also certifies security of device-independent quantum key distribution (QKD) so that an attacker cannot eavesdrop or control the system. We show how this security test can be circumvented in energy-time entangled systems when using standa...

Holt-Oram syndrome (HOS) is a developmental disorder inherited in an autosomal-dominant pattern. Affected organs are the heart and forelimbs with upper extremity skeletal defects and congenital heart malformation. In this study we present three cases of HOS in the same family. In one of these three individuals we detected a transition of C to T (CTG-GTT, V205V) in exon 7 of the TBX5 gene. This ...

Holt-Oram syndrome is an autosomal dominant disorder, characterised by skeletal abnormalities of the upper limb associated with congenital heart defect, mainly atrial and ventricular septal defects. Skeletal defects exclusively affect the upper limbs in the preaxial radial ray distribution and are bilateral and asymmetrical. They range from clinodactyly, absent or digitalised thumb, hypoplastic...