نتایج جستجو برای: hoct1

تعداد نتایج: 63  

Journal: :The Journal of pharmacology and experimental therapeutics 2008
Gerard Minuesa Sergi Purcet Itziar Erkizia Míriam Molina-Arcas Margarita Bofill Nuria Izquierdo-Useros F Javier Casado Bonaventura Clotet Marçal Pastor-Anglada Javier Martinez-Picado

Almost all drugs used in anti-human immunodeficiency virus (HIV)-1 and anticancer therapies require membrane proteins to get into the cell to develop their proper activity. Nevertheless, little is known regarding the expression and activity of specific carriers involved in the uptake of these drugs in immune cells. Here, we assessed the mRNA levels, protein expression profile, and activity of t...

Journal: :Oncology reports 2009
Kenji Negoro Yukio Yamano Dai Nakashima Kengo Saito Ken Nakatani Masashi Shiiba Hiroki Bukawa Hidetaka Yokoe Katsuhiro Uzawa Takeshi Wada Hideki Tanzawa Shigeyuki Fujita

We previously established H-1R cells, a cisplatin (CDDP)-resistant cell line, from H-1 cells, a CDDP-sensitive oral carcinoma cell line. The aim of this study was to identify the molecular mechanism of cross-resistance to antitumor drugs containing a platinum agent in H-1R cells. The 3-(3,4-dimethyl-thiazol-2-yl) 2,5-diphenyltetrazolium bromide (MTT) assay and clonogenecity assay indicated that...

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