Objective(s):Every year, a large number of people lose their lives due to stroke. Stroke is the second leading cause of death worldwide. Surprisingly, recent studies have shown that preconditioning with hyperoxia (HO) increases tissue tolerance to ischemia, ultimately reducing damages caused by stroke. Addressed in this study are beneficial contributions from HO preconditioning into reduced har...

Purpose: To investigate whether surgery for PJI of the hip, the number of procedures and their duration contribute to risk of HO formation. Methods: 56 patients with hip PJI undergoing one-stage (10) or two-stage (46) exchange arthroplasty were matched to 112 patients undergoing revision arthroplasty for aseptic failure based on age, gender, body mass index (BMI), surgical approach (all direct...

just like any other economic field, housing market has two basic foundations which are demand and supply. its obvious that disequilibrum between these foundations, will drasticaly affect the housing affordability and can also lead to wide slump in many markets. that’s why, policy makers usually intend to stimulat the supply by means of providing low intrest loans, low priced land, etc. in this ...

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Heme oxygenase-2 (HO-2) is a critical antioxidative stress enzyme found in endothelial cells and adventitialnerves. This enzyme in conjunction with other HOs (1 and 3) metabolize heme molecule into ferrous iron,carbon monoxide (CO), and biliverdin which is further converted to bilirubin. Both biliverdin and bilirubin arepotent antioxidants, reducing the risk of atherosclerosis...

Background: The length of GT-repeats polymorphic region in the promoter of human Heme oxygenase-1 gene (HO-1) alters the level of its transcriptional activity in response to oxidative stresses. Decreased level of HO-1 protein in the seminal plasma has been reported to be associated with oligospermia and azoospermia in male infertility. This is the first study to investigate the association betw...

The present study examined the heme oxygenase (HO) system in an in vivo murine model of pathological shear stress induced by partial carotid artery ligation. In this model, along with upregulation of vasculopathic genes, HO-1 is induced in the endothelium and adventitia, whereas HO-2 is mainly upregulated in the endothelium. Within minutes of ligation, NF-κB, a transcription factor that upregul...

nigeria has had several housing programmes and policies geared towards the provision of housing her citizens since colonial era to the post-colonial period. the nigerian government had always been directly involved in the provision of housing for the public servants and with the advent of the public-private partnership initiative, the low-income public servants’ acceptability of this new housin...

On 12 April 1961, the russian cosmonaut yuri gagarin (1934–1968) became the first human to leave the confines of Earth and ascend into space. Almost 480 individuals have followed him and, since 31 October 2000, humans have been in space without interruption. this is an enormous technological and scientific achievement; nevertheless, our species has only scratched the surface of what could be ca...

Heme oxygenase (HO) is a cytoprotective enzyme that degrades heme (a potent oxidant) to generate carbon monoxide (a vasodilatory gas that has anti-inflammatory properties), bilirubin (an antioxidant derived from biliverdin), and iron (sequestered by ferritin). Because of properties of HO and its products, we hypothesized that HO would be important for the regulation of blood pressure and ischem...