نتایج جستجو برای: histamine receptor antagonists

تعداد نتایج: 624443  

Journal: :The Journal of pharmacology and experimental therapeutics 2010
Kasper B Hansen Praseeda Mullasseril Sara Dawit Natalie L Kurtkaya Hongjie Yuan Katie M Vance Anna G Orr Trine Kvist Kevin K Ogden Phuong Le Kimberly M Vellano Iestyn Lewis Serdar Kurtkaya Yuhong Du Min Qui T J Murphy James P Snyder Hans Bräuner-Osborne Stephen F Traynelis

N-Methyl-D-aspartate (NMDA) receptors are ligand-gated ion channels that mediate a slow, Ca(2+)-permeable component of excitatory synaptic transmission in the central nervous system and play a pivotal role in synaptic plasticity, neuronal development, and several neurological diseases. We describe a fluorescence-based assay that measures NMDA receptor-mediated changes in intracellular calcium i...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010
Kazuhiro Tamayama Shu-Ling Hoshi Masahide Kondo Ichiro Okubo

Pre-seasonal medication is recommended for cases of cedar pollinosis that are expected to manifest severe symptoms during the season, according to the standard clinical guideline in Japan. This study aims to appraise the value for money of additional costs that accompany the choice of pre-seasonal medication from payer's perspective. Based on the 12 reports of controlled clinical trials with Sy...

Journal: :iranian journal of radiation research 0
h. mozdarani dr. h. mozdarani, department of radiology, school of medical sciences,tarbiat modarres university, p.o.box 14115-111, tehran, iran m. shahidi

background: previous investigations have revealed, cimetidine, a histamine h2-receptor antagonist, show radioprotective effects against gamma- and neutron-induced micronuclei in bone marrow erythrocytes. in this study, the anticlastogenic effects of famotidine and ranitidine, which act similar to cimetidine as histamine h2-receptor antagonists, was investigated. materials and methods : balb/c m...

Journal: :Critical care medicine 2013
Waleed Alhazzani Farhan Alenezi Roman Z Jaeschke Paul Moayyedi Deborah J Cook

BACKGROUND Critically ill patients may develop bleeding caused by stress ulceration. Acid suppression is commonly prescribed for patients at risk of stress ulcer bleeding. Whether proton pump inhibitors are more effective than histamine 2 receptor antagonists is unclear. OBJECTIVES To determine the efficacy and safety of proton pump inhibitors vs. histamine 2 receptor antagonists for the prev...

Journal: :Indian journal of physiology and pharmacology 1986
P K Dey N Mukhopadhaya

At there ambient air temperature range, the rectal temperature changes following infusion of histamine either into lateral ventricle (L.V.) or IVth ventricle (IVth V) were studied. At an ambient temperature range of 19-22 degrees C, hypothermia occurred following histamine infusion either into L.V. or IVth V. Hypothermia elicited from infusion of histamine into L.V. was prevented with pretreatm...

2012
Sangita Biswas Stephen H Benedict Sharon G Lynch Steven M LeVine

Corticosteroids are standard treatment for patients with multiple sclerosis experiencing acute relapse. Because dyspeptic pain is a common side effect of this intervention, patients can be given a histamine receptor-2 antagonist, proton pump inhibitor or antacid to prevent or ameliorate this disturbance. Additionally, patients with multiple sclerosis may be taking these medications independent ...

2015
Robin L. Thurmond

The histamine H4 receptor (H4R) was first noted as a sequence in genomic databases that had features of a class A G-protein coupled receptor. This putative receptor was found to bind histamine consistent with its homology to other histamine receptors and thus became the fourth member of the histamine receptor family. Due to the previous success of drugs that target the H1 and H2 receptors, an e...

Journal: :Journal of King Saud University - Science 2015

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