Abstract Teleost fish exhibit extraordinary cognitive skills that are comparable to those of mammals and birds. Kin recognition based on olfactory visual imprinting requires neuronal circuits were assumed be necessarily dependent the interaction mammalian amygdala, hippocampus, isocortex, latter being a structure teleost lacking. We show teleosts—beyond having hippocampus pallial amygdala homol...

To investigate the effect and related mechanism of propofol anesthesia on pyroptosis in neonatal rat hippocampus. Neonatal rats were divided into a control group (injected intraperitoneally with saline), 80 mg/kg propofol) propofol+MCC950 10 MCC950) administered for 5 d. The day after end drug administration, hippocampi analyzed by transferase dUTP nick labeling assay interleukin beta-1, interl...

background and objectives: studies have documented the morhplogical, neurochemical and functional difference between the dorsal and ventral zones of hippocampus. the aim of this study was to assess the effects of chronic diabetes mellitus type1 on ventral and dorsal zones of hippocampus. methods: experimental diabetes was induced by stereptozotocin at a dose of 60 mg/kg. at the end of 8 weeks ...

the human prefrontal cortex differs from all other mammals: the seat of complex cognition, abstract thinking, planning and future forecasting, and behavioral inhibition. using our prefrontal cortex is a significant energy drain on the body, so despite its impressive capabilities, it’s daily capacity is limited. some researchers estimate a mere 2-3 hours per day of activity depletes the prefront...

introduction: memory and cognitive impairments are some of devastating outcomes of multiple sclerosis (ms) plaques in hippocampus, the gray matter part of the brain. the present study aimed to evaluate the intrahippocampal injection of ethidium bromide (eb) as a simple and focal model to assess cognition and gray matter demyelination. methods: thirty wistar rats were divided into three groups: ...

introduction: cholinergic systems are involved in learning and memory. scopolamine, a muscarinic acetylcholine receptor antagonist, is used as a standard/ reference drug for inducing cognitive deficits in healthy humans and animals. the purpose of this study was to evaluate the effects of scopolamine on avoidance memory and number of neurons in rat’s hippocampus. . methods: thirty five male alb...

background and objective: temporal lobe epilepsy is hallmarked with neuronal degeneration in some areas of hippocampus and mossy fiber sprouting in dentate area. considering some evidences on neuroprotective and antioxidant activity of silymarin (sm), this study was undertaken to evaluate the preventive effect of this agent on structural changes in hippocampus of kainate-epileptic rats. materia...

objective(s) bupropion is an atypical antidepressant that is widely used in smoke cessation under fda approval. the study of synaptic effects of bupropion can help to finding out its mechanism(s) for stopping nicotine dependence. in this study the effects of perinatal bupropion on the population spike (ps) amplitude of neonates were investigated. materials and methods hippocampal slices were pr...