نتایج جستجو برای: high functional autism spectrum disorders

تعداد نتایج: 3218184  

Manal Kassab, Manar Alazzam Shereen Hamadneh, Sirhan Barahmeh

The present study reviewed the literature about intervention programs for Autism Spectrum Disorder (ASD) among children. ASD is a long-term neurodevelopment disorder that is identified as impairment in the context of social communication and interaction, and the predominance of restricted and repetitive patterns of behavior, interests or activities. Intervention programs have objectives such as...

Journal: :The American journal of psychiatry 2015
Marjorie Solomon Michael J Frank J Daniel Ragland Anne C Smith Tara A Niendam Tyler A Lesh David S Grayson Jonathan S Beck John C Matter Cameron S Carter

OBJECTIVE Impairments in learning are central to autism spectrum disorders. The authors investigated the cognitive and neural basis of these deficits in young adults with autism spectrum disorders using a well-characterized probabilistic reinforcement learning paradigm. METHOD The probabilistic selection task was implemented among matched participants with autism spectrum disorders (N=22) and...

Journal: :American journal on intellectual and developmental disabilities 2010
Anna J Esbensen Somer Bishop Marsha Mailick Seltzer Jan S Greenberg Julie Lounds Taylor

Differences between 70 adults with autism spectrum disorders and intellectual disability and 70 age-matched adults with Down syndrome were examined on variables indicative of independence in adult life. Adults with autism spectrum disorder had less residential independence and social contact with friends, had more limited functional abilities and literacy, exhibited more behavior problems, had ...

Journal: :Brain : a journal of neurology 2012
Stephen J Gotts W Kyle Simmons Lydia A Milbury Gregory L Wallace Robert W Cox Alex Martin

Autism spectrum disorders are developmental disorders characterized by impairments in social and communication abilities and repetitive behaviours. Converging neuroscientific evidence has suggested that the neuropathology of autism spectrum disorders is widely distributed, involving impaired connectivity throughout the brain. Here, we evaluate the hypothesis that decreased connectivity in high-...

Journal: :JAMA 2003
Sallie Bernard

CONTEXT Mercuric compounds are nephrotoxic and neurotoxic at high doses. Thimerosal, a preservative used widely in vaccine formulations, contains ethylmercury. Thus it has been suggested that childhood vaccination with thimerosal-containing vaccine could be causally related to neurodevelopmental disorders such as autism. OBJECTIVE To determine whether vaccination with a thimerosal-containing ...

Journal: :The American journal of psychiatry 2010
Michael Feyder Rose-Marie Karlsson Poonam Mathur Matthew Lyman Roland Bock Reza Momenan Jeeva Munasinghe Maria Luisa Scattoni Jessica Ihne Marguerite Camp Carolyn Graybeal Douglas Strathdee Alison Begg Veronica A Alvarez Peter Kirsch Marcella Rietschel Sven Cichon Henrik Walter Andreas Meyer-Lindenberg Seth G N Grant Andrew Holmes

OBJECTIVE Research is increasingly linking autism spectrum disorders and other neurodevelopmental disorders to synaptic abnormalities ("synaptopathies"). PSD-95 (postsynaptic density-95, DLG4) orchestrates protein-protein interactions at excitatory synapses and is a major functional bridge interconnecting a neurexinneuroligin-SHANK pathway implicated in autism spectrum disorders. METHOD The a...

2012
Carl J. Dunst Carol M. Trivette Deborah W. Hamby

Incorporating the interests and preferences of young children with autism spectrum disorders into interventions to promote prosocial behavior and decrease behavior excesses has emerged as a promising practice for addressing the core features of autism. The efficacy of interest-based early intervention practices was examined in a meta-analysis of 24 studies including 78 children 2 to 6 years of ...

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