نتایج جستجو برای: hexachlorophene

تعداد نتایج: 112  

Journal: :The Journal of the Society of Chemical Industry, Japan 1962

Journal: :Antimicrobial agents and chemotherapy 1974
J J Frederick T R Corner P Gerhardt

Hexachlorophene (HCP) inhibits both endogenous and exogenous respiration (oxygen uptake) in Bacillus megaterium, without sparing by any of several substrates. The inhibition is maximal when the cells are treated with 8 mug of HCP per mg of cells (dry weight), which corresponds to the minimal lethal dose. Levels as low as 2 mug/mg are inhibitory but not lethal. HCP also inhibits the respiration ...

Journal: :British medical journal 1973
J N Bruun C O Solberg

The influence of hexachlorophane disinfection on the bacterial hand flora of hospital personnel has been examined. Hexachlorophane effectively reduced the total number of bacteria and the staphylococcal carriage. Gram-negative bacilli were isolated from 18.8% of the personnel, and 13% of the carriers continued to carry Gram-negative bacilli for more than six months. The carrier rate was signifi...

Journal: :Antimicrobial agents and chemotherapy 1976
K H Swamy A Joshi G R Rao

Miconazole, a potent antifungal agent, labilizes rat liver lysosomes. Its labilizing effect is followed by measuring the release of lysosomal hydrolases, namely, acid phosphatase, beta-glucuronidase, and arylsulfatase A. The effect of miconazole is concentration dependent in the range of 10(-5) to 1.2 x 10(-4) M. However, at higher concentrations, miconazole inhibits enzyme release but does not...

Journal: :Antimicrobial agents and chemotherapy 2004
Bernd Hutter Christoph Schaab Sebastian Albrecht Matthias Borgmann Nina A Brunner Christoph Freiberg Karl Ziegelbauer Charles O Rock Igor Ivanov Hannes Loferer

We have generated a database of expression profiles carrying the transcriptional responses of the model organism Bacillus subtilis following treatment with 37 well-characterized antibacterial compounds of different classes. The database was used to build a predictor for the assignment of the mechanisms of action (MoAs) of antibacterial compounds by the use of support vector machines. This predi...

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