The NIH 3T3 line of mouse fibroblasts undergoes "spontaneous" transformation in culture, exhibited in the development of foci of transformed cells overgrowing the confluent monolayer. Evidence is provided here to support the proposition that the spontaneous generation of individual transformed variants is a product of epigenetic induction by various types of growth inhibition. Novel transformed...

Should human beings who have been granted basic rights be allowed to bargain them away? In some countries, most prominently in China, special export zones exist where workers are required to give up several of their rights in order to be employed. Are there serious objections to such renouncements? The first part of this paper discusses some of the pros and cons. In the second part, the results...