According to the amyloid cascade hypothesis, accumulation of the amyloid peptide Aβ, derived by proteolytic processing from the amyloid precursor protein (APP), is the key pathogenic trigger in Alzheimer's disease (AD). This view has led researchers for more than two decades and continues to be the most influential model of neurodegeneration. Nevertheless, close scrutiny of the current evidence...

A muscle will not function properly if the bone to which it is attached is broken or is in a state of degeneration. The same is true of the Christian life. Orthodoxy serves as the skeletal framework for the saint of God. If that framework is faulty and does not affirm truth, the result will be a defective lifestyle. In the Epistle to the Colossians Paul demonstrated this point. The Colossian co...

It is widely believed that translation occurs only in the cytoplasm of eukaryotes, but recent results suggest some takes place in nuclei, coupled to transcription. Support for this heterodoxy comes from studies of the nonsense-mediated decay (NMD) pathway; this pathway probably uses ribosomes to proofread messenger RNAs. We find components of the machineries involved in transcription, translati...

In standard Albanian studies and Western scholarship, including both the work of religious and political activists and that of less ‘interested’ lay people, historical and textual fact-finding efforts have only confirmed and indeed perpetuated the myth that the thinking of Naim Frashëri was formed and dominated by Bektashism and that his ‘Albanianism’ had a Bektashi foundation. The author inten...