The title compound, C(20)H(23)N(3)O(4)S, is an important biologically active heterocyclic compound. The five-membered ring is oriented with respect to the six-membered rings at dihedral angles of 78.60 (3) (trimethoxyphenyl ring) and 71.57 (3)° (methoxyphenyl ring). In the crystal structure, inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into infinite chains along the c axis.

Present communication deals with the synthesis and characterization of various spiro thiazolinone heterocyclic compounds. 4-(4-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-ylsulfonyl)phenyl)-1-thia-4-azaspiro[4.5]decan-3-one (5) was synthesized by facile and fast heterocyclization reaction, which further underwent condensation with 4-chlorobenzaldehyde to afford 2-(4-chlorobenzylidene)-4-(4-(6,7-dihy...

Functionalization of N-heterocyclic carbenes (NHCs) has an important influence on their stability, Lewis donor, and acceptor properties. In this study, we report on the selective functionalization of a four-membered N-heterocyclic bis-silylene (2,6-Ar2C6H3NSi:)2 (1) (Ar = 2,4,6-iPr3C6H2) with mono-oxygen sources N2O and Me3NO. Treatment of 1 with N2O results in the selective formation of mono-s...

A new heterocyclic compounds(II-V)were synthesized through a reaction of compound(I) with urea,thiourea,hydrazine hydrate, and hydroxylamine hydrochloride series Schiff bases(VIa-d) (VIIa-d) were from( II) (III).The prepared compounds characterized by (FT-IR) spectrum. Physical properties the recorded their mesomorphic phases investigated.

The title compound, [Cu₂Cl₄(C₁₄H₁₄N₂)₂], is a new polymorph of a previously reported compound [Dehghanpour et al. (2011 ▶). Acta Cryst. E67, m1296]. The current polymorph was obtained from an acetonitrile solution of the title compound. Like the first polymorph, it is monoclinic (space group P2₁/c). The unique Cu(II) ion in the title centrosymmetric dinuclear complex is in a distorted trigonal-...

Established from previous studies, a heterocyclic pyrrolopyrimidine (PyP) compound increases endogenous stem cell proliferation. Here, we utilized a topical PyP to increase cell proliferation of cells responsible for hair production. Varying doses (0.75, 1.5, 3.0 mg/ml) were applied to shaved, dorsal regions of mice for 5 consecutive days. Bromodeoxyuridine (100 mg/kg/day, i.p.) was injected on...

The synthesis and analytical applications of the new heterocyclic ligand are described. The complexation reaction of the ligand with some cations was studied in aqueous methanol at room temperature using the spectrophotometric method. Results revealed that only the absorption spectra of the Fe (III)–ligand complex show a high redshift of the absorption maximum in the aqueous methanol soluti...

3-Mercapto-1,2,4 benzotriazine (1) was methylated by methyl iodide in the presence of base to afford 1,2-dihydro-3-methyhercapto-1, 2,4 benzotriazine (2). The latter was reacted with hydrazine hydrate to give the corresponding 3-hydrazine derivative (3). Compound (3) on condensation with phenacyl bromide gave 3- phenacyl hydrazino l,2,4-benzotriazine (4). PPA cyclization of the ketone (4) ...