The Herpesviridae comprise a large class of animal viruses of considerable public health importance. Of the Herpesviridae, replication of herpes simplex virustype-1 (HSV-1) has been the most extensively studied. The linear 152-kbp HSV-1 genome contains three origins of DNA replication and approximately 75 open-reading frames. Of these frames, seven encode proteins that are required for originsp...

Herpesviruses of humans and animals cause severe diseases that influence not only the health and epidemiological status but are also economically important in the context of food production. The members of Herpesviridae are host specific agents that also share many properties that potentially make them capable of crossing the species barriers. The objective of presented review paper was to summ...

In a recent paper Chen et al., using the longitudinal National Health Insurance Research of Taiwan database, compared 41 229 patients with peptic ulcer disease (PUD) and 41 229 matched controls. Because the cumulative incidence of varicella zoster infection in PUD patients was significantly higher compared with the control cohort (P< 0.001), the authors concluded that patients with PUD were at ...