Pet Ether, Chloroform, and Methanol extracts of roots of Blue and White flowered varieties of Clitoria ternatea (CT) were studied for their hepatoprotective potential against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. The hepatoprotective activity was assessed using various biochemical parameters like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate tr...

Free radicals include both Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS).When free radicals are produced in a regulated manner in a healthy human body it is scavenged efficiently by antioxidant defense system. But excess generation of pro-oxidants by continuous chain reaction in the form of ROS and RNS cause several human diseases. The shift of the balance in the favour of p...

BACKGROUND Natural products with therapeutic properties such as plants, minerals, and animal products, for many years, were the main sources of drugs for the treatment of numerous diseases; hence selection of Lawsonia inermis L. (Henna) to study its hepatoprotective activity was considered. OBJECTIVES This was an attempt to evaluate the hepatoprotective effect of L. inermis leaves' methanolic...

ricinus communis linn. (euphorbiaceae) is a soft wooded tree widely prevalent throughout tropics regions of the world which have a warm temperature. in the indian system of medicine, the leaves, roots and seed oil of this plant have been used for the treatment of inflammation and liver disorders for a long time. in the present study, the protective effects of ethanol extract of ricinus communis...

objective(s):the current study was aimed to determine the bioactive constituents and biological effects of the crataegus monogyna ethanolic extracts from bark, leaves and berries on hypercholesterolemia. materials and methods: oleanolic acid, ursolic acid, quercetin and lupeol concentrations were quantified by hplc. total phenol content and radical scavenging activity of extracts were also meas...

conclusions the present study indicated a hepatoprotective effect of loe in diabetic rats. background plants have been the basis for medical treatments throughout much of human history. although the active compounds of many herbal drugs are unknown, they have been widely prescribed by traditional medicine practitioners due to their beneficial effects and low cost. although the primary feature o...

Hepatoprotective effects of the lipid flower pollen extract (LEPK) in paracetamol intoxication in mice were shown. Normalisation of A1AT and LDH--biochemical indicators of necrotic changes in the hepatic cells, and high protection ultrastructural cell organelle such as mitochondrion substantially testifies to the hepatoprotective effect of investigated lipid flower pollen extract on the hepatic...

Many hepatoprotective non-chemical preparations have been recommended as complementary medicine for the treatment of liver disorders. We have utilized a well-defined model of liver injury to study the efficacy of GLU-9599 (a oral bioavailable glutathione-based compound added with selenium, L-cysteine and vitamin C) designed to support liver detox function. Wistar albino rats were divided into f...

This study was designed to determine the antioxidant and hepatoprotective effect of nbutanol soluble fractions of Albizzia lebbeck The various extracts were prepared and extracts containing flavanoids, tannins and saponins (Methanolic extract) was selected for isolation of chemical constituents. nbutanol soluble fractions of extract (BFALB) and leaf extract (BFALL) were selected for screening o...

As a part of our search for hepatoprotective compounds from Lycium chinense fruits, three new pyrrole derivatives (1-3) were isolated. These compounds and a related synthetic methylated compound (4) were evaluated for their biological activity and structure-activity relationship, and compounds 1 and 2 showed hepatoprotective effects comparable to silybin at the concentration of 0.1 microM (64.4...