Objective: Hemophilia is a genetic bleeding disorder results from a deficient in synthesis of a protein needed for blood clotting. The number of people with hemophilia in the United States is about 20,000. Iran having the ninth largest Hemophilia population in the world. Hemophilia lead to many psychological and physiological complications. Therefore, this study aimed to evaluate the effectiven...

1University of Health Sciences Faculty of Medicine, Department of Hematology, Lahore, Pakistan 2University of Health Sciences Faculty of Medicine, Department of Biochemistry, Lahore, Pakistan 3Quaid-i-Azam University Faculty of Biological Sciences, Department of Biochemistry, Islamabad, Pakistan 4University of Health Sciences of Medicine, Department of Human Genetics and Molecular Biology, Laho...

6.5 Range of Application, Dosage, Mode of Administration 6.5.1 General Information 6.5.2 Indications for Replacement Therapy Using Factor Concentrates 6.5.3 Dosage, Mode of Administration 6.5.3.1 Replacement in Children with Hemophilia A, B or von Willebrand Syndrome 6.5.3.2 Replacement in Adults with Hemophilia A, B or von Willebrand Syndrome 6.5.3.3 Indications and Recommended Doses for Treat...

Factor VIII activity and factor VIII related--or Willebrand--antigen were studied in 49 known carriers of haemophilia A and 31 normal women, and the data were analysed by four statistical approaches. Sixteen per cent of normals and 18% of carriers were misclassified, overlapping with the other group. Although the percentage of carriers detected is higher when taking into account the results of ...