Background: Treatments for severe sepsis are limited, and its morbidity and mortality, especially from Gramnegative organisms, continues to be significant. Gram-negative organisms release endotoxin, which initiates inflammatory and coagulation cascades, resulting in end-organ dysfunction in patients. Polymyxin B hemoperfusion filters bind endotoxin. Objective: To assess the efficacy of polymyxi...

The objective: to study in vitro adsorption properties of various devices for selective lipopolysaccharide (LPS) adsorption. Subjects and Methods: Various methods closed circuit circulating bovine serum endotoxin solutions were used. was perfused using an LPS sorption device 240 min. Serum samples collected before the start perfusion, 30, 60, 120, 150, minutes after circulation. concentrations ...

Historically, mortality after Amanita mushroom ingestion has ranged from 50% to 90%. Prompt diagnosis is imperative, and aggressive therapeutic measures must be instituted quickly to improve the outcome. We report successful treatment of two cases of A. virosa poisoning by use of combined therapies, including thioctic acid and hemoperfusion.

Background: Now hemoperfusion has not been used for the treatment of severe neonatal jaundice, and bilirubin adsorbent with high adsorption and safety should be the prerequisite for the use. Objectives: To investigate the adsorption of six kinds of current adult/industrial bilirubin adsorbents from severe neonatal jaundice plasma, then screen the best one with highest adsorption for further eva...

BACKGROUND Blood hemoperfusion with resin adsorption can clean larger molecules that exceed the molecular weight cutoff of combined continuous veno-venous hemofiltration (CVVH). Hence blood hemoperfusion with resin adsorption combined CVVH (HP+CVVH) has higher ability of mediator clearance, and can improve clinical outcomes in theory. This study aimed to investigate the effect of blood hemoperf...