Constitutional pericentric inversion of chromosome 9 [inv(9)] occurs in 0.8 to 2% of the normal population and has long been considered a normal variant. It is controversial whether inv(9) is a predisposing factor for acute leukemia (AL). The effect of inv(9) on bone marrow (BM) recovery after stem cell transplantation or chemotherapy is undetermined. Between March 2001 and December 2008, the c...

TO THE EDITOR: In their recent editorial on the disappointing disagreement between two World Anti-Doping Agency (WADA)-accredited laboratories evaluating samples for detecting recombinant human erythropoietin (Epo) in urine, Delanghe and Joyner (4) concluded that blood-based indirect Epo tests offer an interesting alternative (2). This is ideally true, considering that the urine test is proven ...

Aim: To determine the frequency of non malignant hematological causes of pancytopenia. Bone marrow examination of 148 cases of suspected hematological disorders was carried out in a DHQ KDA Hospital, Kohat from Jan. 2011to Dec. 2013. Results: Among the non malignant hematological disorders, megaloblastic anemia was the most common disorder i.e., (18.2%) followed by aplastic anemia (8.8%), ITP (...

Generally, clinical presentations of Graves' disease range from asymptomatic disease to overt symptomatic hyperthyroidism with heat intolerance, tremor, palpitation, weight loss, and increased appetite. However, atypical presentation of Graves' disease with hematological system involvement, notably pancytopenia, is distinctly uncommon. Hereby, we present and discuss a series of three untreated ...

TO THE EDITOR: In their recent editorial on the disappointing disagreement between two World Anti-Doping Agency (WADA)-accredited laboratories evaluating samples for detecting recombinant human erythropoietin (Epo) in urine, Delanghe and Joyner (4) concluded that blood-based indirect Epo tests offer an interesting alternative (2). This is ideally true, considering that the urine test is proven ...

Cellular components of the blood reflect specific changes in an organ or body system or more often, a general response of the individual to some physiological or pathological conditions. In this chapter, we will review the main physiological factors that should be considered when interpreting equine hematological profiles. The interpretation of the hematological profile in conjunction with hist...

The lack of updated neonatal reference values for hematological parameters impacts significantly with clinical management of both healthy and sick newborns. The present pilot study was thus aimed at assessing updated hematological Italian reference values in late preterm and term newborns. From January 2004 to December 2008 hematological laboratory tests were performed in 1175 newborns (820 hea...

Hematological emergencies are defined as acute life-threatening conditions in hematological diseases due to benign blood disorders or hematological malignancies or as a result of its treatment. This article deals of the most common emergencies encountered by hematologists. Emerging clinical situations, predictable or not, are common in the treatment of hematological diseases. However, the rapid...