BACKGROUND AND STUDY AIMS Gastrointestinal bleeding in children and adolescents accounts for up to 20 % of referrals to gastroenterologists. Detailed management guidelines exist for gastrointestinal bleeding in adults, but they do not encompass children and adolescents. The aim of this study was to assess gastrointestinal bleeding in pediatric patients and to determine an investigative manageme...

A 63-year-old woman was hospitalized after 2 episodes of mucoid, maroon-colored stools. She denied any prior or current episodes of abdominal pain, vomiting, fever, or recent travel. She was hemodynamically stable without significant drop in hematocrit. Colonoscopy revealed a 5-cm polypoid mass in the ascending colon with ulceration and fat eroding through the mucosa (Figure 1). The colonicsegm...

We present a case of a 61-year-old woman with end-stage renal disease (ESRD) who developed painless hematochezia following initiation of anticoagulation. Work-up revealed a large ulceration in the sigmoid colon, and histologic images revealed sevelamer crystals embedded in the colonic mucosa, consistent with sevelamer crystal-mediated injury. This is a novel cause of gastrointestinal hemorrhage...

Common causes of lower gastrointestinal bleeding include diverticular disease, vascular disease, inflammatory bowel disease, neoplasms, and hemorrhoids. Lower gastrointestinal bleeding of appendiceal origin is extremely rare. We report a case of lower gastrointestinal bleeding due to angiodysplasia of the appendix. A 72-year-old man presented with hematochezia. Colonoscopy showed active bleedin...

levels (75.10 U/mL). Sigmoidoscopy was performed, showing a polypoid, fungating mass with colonic obstruction in the rectum, located 11 cm from the anal verge (Fig. A). Chronic inflammation with ulceration and epithelial hyperplasia were observed in the mucosal layer of endoscopic biopsies. A CT scan of the abdomen and pelvis revealed an illdefined enhancing lesion in the rectum, abutting the u...