The reaction o f 5'-CMP with methyl, ethyl, «-propyl and isopropyl iodides gave predomi­ nantly ribose alkylated products. Various alkylated derivatives have been characterized using UV spectroscopy, paper electrophoresis, 'H N M R and FAB (negative) mass spectroscopic techniques. Under strongly alkaline conditions the 2'-0-alkylated derivatives are synthesized in maximal yields. Isopropylation...

a-Methoxyand a-ethoxyketones, as important intermediates in organic synthesis and flavor compounds in food chemistry, were synthesized by deprotonation of N-(1-alkoxy-2-propylidene)isopropylamine, prepared by condensation of the corresponding a-alkoxyacetone with isopropylamine, and subsequent reaction of the corresponding 1-azaallylic anions with alkyl halides to afford a¢-alkylated, a-alkylat...

The use of naturally occuring polyphenols as hydrogen bond donors in supramolecular liquid crystals was investigated using alkylated azopyridines or stilbazoles acceptors.

Different compounds have been reported as biomarkers of a smoking habit, but, to date, there is no appropriate biomarker for tobacco-related exposure because the proposed chemicals seem to be nonspecific or they are only appropriate for short-term exposure. Moreover, conventional sampling methodologies require an invasive method because blood or urine samples are required. The use of a microtra...

1. Study corroborates our analysis done in October-November, 2009 that the UCIL site is heavy contaminated with chlorinated benzene compounds, organochlorine pesticides, carbmate pesticides (Carbaryl and Aldicarb. It also confirms that this contamination has nothing to do with the gas accident, but is caused by UCC/UCIL dumping and disposing off waste indiscriminately on the site. All pesticide...

1. Apparently all disulphide bridges of transferrin and conalbumin were broken by reduction-alkylation, whereas sulphitolysis resulted in incomplete cleavage of disulphide bonds. 2. The molecular weights of reduced-alkylated and sulphitolysed transferrin and reduced-alkylated conalbumin were identical with those of native proteins in a number of solvents, indicating that these proteins exist as...

A monoclonal antibody to vasoactive intestinal polypeptide (VIP) was reduced and alkylated and its light and heavy chains were purified by denaturing gel filtration. Following renaturation, the light chain displayed sequence-specific binding of VIP. The specific VIP binding activity of several fractions spanning the light chain peak recovered from the gel filtration column was constant, the lig...

Benzene, an important component in gasoline, is a widely distributed environmental contaminant that has been linked to known health effects in animals and humans, including leukemia. In Mexico City, environmental benzene levels, which may be elevated because of the heavy traffic and the poor emission control devices of older vehicles, may pose a health risk to the population. To assess the pote...

Diketopyrrolopyrroles are N-alkylated under mild conditions using secondary aliphatic and benzyl type alcohols.

A new case of mu heavy chain disease is Appreciable amounts of kappa chains described. The patient, a 48-yr-old Italian were also detected in the urine. The mu housewife, suffered from chronic lymphochain disease protein had a molecular cytic leukemia of 3 yr duration with weight of approximately 54,000 and a anemia and hepcstosplenomegaly, but no heterogeneous NH2 terminus, alanine peripheral ...