holt-oram syndrome is an autosomal dominant disorder, characterised by skeletal abnormalities of the upper limb associated with congenital heart defect, mainly atrial and ventricular septal defects. skeletal defects exclusively affect the upper limbs in the preaxial radial ray distribution and are bilateral and asymmetrical. they range from clinodactyly, absent or digitalised thumb, hypoplastic...

Holt-Oram syndrome is an autosomal dominant disorder, characterised by skeletal abnormalities of the upper limb associated with congenital heart defect, mainly atrial and ventricular septal defects. Skeletal defects exclusively affect the upper limbs in the preaxial radial ray distribution and are bilateral and asymmetrical. They range from clinodactyly, absent or digitalised thumb, hypoplastic...

OBJECTIVE Congenital heart diseases are among the most frequent major congenital anomalies. One of the suspected reasons for congenital heart defects is overweight and obesity of mother during prepregnancy and pregnancy. We studied the relationship between maternal overweight and obesity and the risk of congenital anomaly. METHODS All of children with congenital heart defect (164 infants with...

OBJECTIVE To analyse the spectrum of congenital heart malformations, the frequency of extracardiac malformations, and the proportion of chromosome aberrations among fetuses sent for necropsy. MATERIAL Necropsies were performed on 815 fetuses-448 induced abortions (55%), 220 spontaneous abortions (27%), and 147 stillbirths (18%)-during a seven year period (1991-97) in the department of patholo...

Background: Cor triatriatum is a rare congenital cardiac malformation. Prevalence only around 0.1% of the diagnosed cardiovascular malformations. Historically prevalence has been described 0.4% in autopsies patients with heart disease. It characterized by presence membrane, usually, endocardium and fibro-muscular tissue within one atrial chambers, dividing it into two, thereby giving appearance...

Introduction: Along with advances occurring in cardiopulmonary bypass (CPB) including improved anesthesia intubation and early surgical interventions, it has become possible to correct life-threatening congenital heart anatomic abnormalities in patients. Our study aimed to collect information from one of the most important centers of pediatric cardiac surgery in Iran since there is limited info...

The heart sounds of 20 patients with uinecomiplicated atrial septal defect have been analyzed, and the deviations from a normal control group were noted. Following complete closure of the defect 11 patients have been restudied, and the changes produced in the heart sounds by closure of the defect are discussed. By comparison of pre-operative and postoperative heart sounds and electrocardiograms...