نتایج جستجو برای: health endpoint
تعداد نتایج: 997936 فیلتر نتایج به سال:
The Endpoint Theorem links the existence of a sequence (curve), without accumulation points, in manifold to an open embedding that so image given (curve) has unique endpoint. It plays fundamental role theory Abstract Boundary as it implies there is always boundary point represent endpoint such sequences and curves. will be interest researchers analysing specific spacetimes shows how construct c...
Cervical intraepithelial neoplasia (CIN) represents a spectrum of epithelial changes that provide an excellent model for developing chemopreventive interventions for cervical cancer. Possible drug effect surrogate endpoint biomarkers are dependent on the agent under investigation. Published and preliminary clinical reports suggest retinoids and carotenoids are effective chemopreventive agents f...
BACKGROUND Cardiovascular diseases are the major cause of death globally and represent a major economic burden on health care systems. Positive effects of disease management programs have been shown for patients with heart failure (HF). Remote monitoring and telemonitoring with active intervention are beneficial in atrial fibrillation (AF) and therapy-resistant hypertension (TRH), respectively....
BACKGROUND Bacterial pneumonia is a leading cause of illness and death worldwide, but quantifying its burden is difficult due to insensitive diagnostics. Although World Health Organization (WHO) protocol standardizes pediatric chest radiograph (CXR) interpretation for epidemiologic studies of bacterial pneumonia, its validity in adults is unknown. METHODS Patients (age ≥ 15 years) admitted wi...
In a working group of the National Institutes of Health focusing on biomarkers and surrogate end-points, a biomarker was defined as a “characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention” [1]. In the same document, the National Institutes of Health defined a clinica...
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