Migraine is a primary headache which is very common in the society. Although it is usually starts in a salient point in life span of an individual diagnostically, the repetition of acute stress response such as sleep abnormalities, anxiety, and depression are not new in this population. Therefore, they have had almost a long diary of these abnormalities. In order to understand the role/s of str...

background: migraine is a chronic disease that affects nearly 6% of men and 18% of women worldwide. there are various drugs, which can successfully decrease migraine symptoms and frequency of migraine attacks, but these drugs usually are expensive. hence, this study aimed to assess the effects of pyridoxine  supplementation on severity, frequency and duration of migraine attacks as well as head...

migraine is a primary headache which is very common in the society. although it is usually starts in a salient point in life span of an individual diagnostically, the repetition of acute stress response such as sleep abnormalities, anxiety, and depression are not new in this population. therefore, they have had almost a long diary of these abnormalities. in order to understand the role/s of str...

OBJECTIVE To evaluate the onset of efficacy of TEV-48125, a monoclonal antibody against calcitonin gene-related peptide, recently shown to be effective for the preventive treatment of chronic migraine (CM) and high-frequency episodic migraine. METHODS A randomized placebo-controlled study tested once-monthly injections of TEV-48125 675/225 mg or 900 mg vs placebo. Headache information was cap...

BACKGROUND Headache is one of the most prevalent investigated complaints in the neurology clinics and is the most common pain-related complaint worldwide. Stress is a significant factor that causes and triggers headaches. Since healthcare practitioners experience a lot of stress in their careers, they are more prone to headaches. OBJECTIVES This study was designed to evaluate and compares the...

Migrainous headache is determined by pathogenetic mechanisms that are also able to affect the peripheral and/or central vestibular system, so that vestibular symptoms may substitute and/or present with headache. We are convinced that there can be many different manifestations of vestibular disorders in migrainous patients, representing true different clinical entities due to their different cha...

BACKGROUNDS Tension-type headache is a common psychosomatic disease. However, diurnal variation of headache is yet to be clarified, perhaps due to the lack of an appropriate method to investigate it. Like other painful diseases, it would be helpful to know if there is diurnal variation in tension-type headaches, both for managing headaches and understanding their pathophysiology. The aim of thi...