The author of the article aims to explain world literature through such concepts as the concept of Hamletism and the character of Hamlet in relation to selected works of Russian Romanticism, in particular, the beginning of realism and symbolism as an outstanding current of the Silver Age. Subject of a careful comparative analysis is the works of Mikhail Lermontov ("Demon" and "Ma...

In this work, by use of a formalism similar to formalism of the quantum Zeno effect (decrease of the decay probability of an unstable quantum system by frequent measurements) and quantum anti-Zeno effect (increase of the decay probability of an unstable quantum system by frequent measurements), we introduce so-called quantum Hamlet effect. It represents a complete destruction of the quantum pre...

1. Laertes is about to stab Hamlet. Claudius, watching from the wings, desperately wants Laertes to stab Hamlet and has implanted a device in Laertes’ brain that, if activated, will force him to stab Hamlet. Claudius intends to activate the device if it appears that Laertes will change his mind at the last moment. Laertes, however, stabs Hamlet of his own accord and Claudius’s device is never a...

In the first follow up survey, we identified the set of hamlets in each village that had at least one targeted beneficiary and had not been randomly selected to be surveyed in the previous experiment; we then randomly selected one hamlet from this set. Within each hamlet, we selected 8 households to be surveyed for a total of 4,571 households. Of these 8 households, we oversampled beneficiaries...

Members of the SWI/SNF chromatin-remodeling complex are among the most frequently mutated genes in human cancer, but how they suppress tumorigenesis is currently unclear. Here, we use Drosophila neuroblasts to demonstrate that the SWI/SNF component Osa (ARID1) prevents tumorigenesis by ensuring correct lineage progression in stem cell lineages. We show that Osa induces a transcriptional program...

Recently, the anticancer activity of human α-lactalbumin made lethal to tumor cells (HAMLET) has been linked to its increased membrane affinity in vitro, at neutral pH, and ability to cause leakage relative to the inactive native bovine α-lactalbumin (BLA) protein. In this study, atomic force microscopy resolved membrane distortions and annular oligomers (AOs) produced by HAMLET when deposited ...

Some natural proteins induce tumor-selective apoptosis. α-Lactalbumin (α-LA), a milk calcium-binding protein, is converted into an antitumor form, called HAMLET/BAMLET, via partial unfolding and association with oleic acid (OA). Besides triggering multiple cell death mechanisms in tumor cells, HAMLET exhibits bactericidal activity against Streptococcus pneumoniae. The existing methods for prepa...

We used molecular approaches to study the status of speciation in coral reef fishes known as hamlets (Serranidae: Hypoplectrus). Several hamlet morphospecies coexist on Caribbean reefs, and mate assortatively with respect to their strikingly distinct colour patterns. We provide evidence that, genetically, the hamlets display characteristics common in species flocks on land and in freshwaters. S...