Blood transfusion is a life-sustaining procedure. But there are several hurdles in safe blood administration which can cause transmitted infections (TTI) and acute reactions even death. Besides, human errors anywhere the chain add fuel to fire. borne Infections like Hepatitis B C highly prevalent Pakistan affecting about 7.4% of general population. Among reactions, Febrile nonhemolytic reaction...

The Serious Hazards of Transfusion (SHOT) UK confidential haemovigilance reporting scheme began in 1996. Over the 16 years of reporting, the evidence gathered has prompted changes in transfusion practice from the selection and management of donors to changes in hospital practice, particularly better education and training. However, half or more reports relate to errors in the transfusion proces...

Arthropod-borne viruses (arboviruses) are a growing threat to global health. Complex vector-virus-host interactions lead to unpredictable epidemiological patterns. Difficulties in accurate surveillance including imperfect diagnostic tools impair effective response to outbreaks. With arboviral infections causing a wide spectrum of disease severity, from asymptomatic infection to fatal neuroinvas...

A centralized hemovigilance program was launched in the country on December 10, 2012, to assure patient safety and promote public health through a well‐structured program for monitoring of adverse reactions associated with blood and blood product transfusions. The National Institute of Biologicals (NIB), Noida, is the National Co‐ordinating Centre. The Haemovigilance Programme of India (HvPI) w...

OBJECTIVE To determine the frequency and type of Acute Transfusion Reactions (ATRs) occurring in inpatients, reported to the transfusion service at Aga Khan University Hospital, Karachi, Pakistan. METHODS This was a three years and seven months (from January 2005 till July 2008) retrospective review of all the transfusion reactions that were reported to the transfusion service at Aga Khan Uni...

BACKGROUND To assess the impact of safety measures, we compared reporting rates of transfusion-related reactions before and after the implementation of six measures in 1999, 2004, 2006, 2008 and 2009. METHODS Reporting rates of transfusion-transmitted bacterial infection (TTBI), viral infection (TTVI) and immune-mediated transfusion-related acute lung injury (TRALI) were calculated on the bas...