نتایج جستجو برای: gyrate atrophy

تعداد نتایج: 36545  

2008
David Kronus

Every k-interval Boolean function f can be represented by at most k intervals of integers such that vector x is a truepoint of f if and only if the integer represented by x belongs to one of these k (disjoint) intervals. Since the correspondence of Boolean vectors and integers depends on the order of bits an interval representation is also specified with respect to an order of variables of the ...

Journal: :The Tohoku Journal of Experimental Medicine 1981

Journal: :The Journal of clinical investigation 1980
I Sipilä O Simell P Arjomaa

Patients with gyrate atrophy of the choroid and retina have 10- to 20-fold increased ornithine concentrations in body fluids and significantly reduced activity of ornithine aminotransferase in lymphocytes and cultured fibroblasts. We administered intravenous arginine to six patients and six controls to study in vivo inhibition by high ornithine concentrations of arginine-glycine transamidinase,...

Journal: :Investigative ophthalmology & visual science 1988
G Inana Y Hotta C Zintz K Takki R G Weleber N G Kennaway K Nakayasu A Nakajima T Shiono

A generalized deficiency in the mitochondrial enzyme, ornithine aminotransferase (OAT: EC 2.6.1.13), is the hallmark of gyrate atrophy (GA), a hereditary degenerative disease of the choroid and retina of the eye that leads to blindness. A human OAT cDNA, previously constructed and characterized in our laboratory, and anti-human OAT antibody were used as probes to examine the OAT gene, mRNA and ...

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