GW bodies (or P-bodies) are cytoplasmic granules containing proteins involved in both mRNA degradation and storage, including the RNA interference machinery. Their mechanism of assembly and function are still poorly known although their number depends upon the flux of mRNA to be stored or degraded. We show here that silencing of the translational regulator CPEB1 leads to their disappearance, as...

It has been reported that treatment of cultured human skeletal muscle myotubes with the peroxisome proliferator-activated receptor-delta (PPARdelta) activator GW-501516 directly stimulates glucose transport and enhances insulin action. Cultured myotubes are minimally responsive to insulin stimulation of glucose transport and are not a good model for studying skeletal muscle glucose transport. T...

LetGw be a weighted graph. The number of the positive, negative and zero eigenvalues in the spectrum of Gw are called positive inertia index, negative inertia index and nullity of Gw, and denoted by i+(Gw), i−(Gw), i0(Gw), respectively. In this paper, sharp lower bound on the positive (resp. negative) inertia index of weighted bicyclic graphs of order n with pendant vertices is obtained. Moreov...

During ‘Type III’ ELMs on Alcator C-Mod, electron cyclotron emission (ECE) diagnostics show brief signal drops of second harmonic X-mode and signal increases of fundamental harmonic O-mode. These are explained in terms of refraction effects and found to be useful to infer the associated ELM geometrical dimensions. A new ray tracing code, which can accommodate poloidal variations, has been devel...

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This paper gives a new definition of general weighted (GW) fairness and shows how this can achieve various fairness definitions, such as those mentioned in the ATM Forum TM 4.0 specifications. The GW fairness can be achieved by calculating the ExcessFairshare (weighted fairshare of the left over bandwidth) for each VC. We show how a switch algorithm can be modified to support the GW fairness by...

GW bodies, also known as mammalian P-bodies, are cytoplasmic foci involved in the post-transcriptional regulation of eukaryotic gene expression. Recently, GW bodies have been linked to RNA interference and demonstrated to be important for short-interfering-RNAand microRNA-mediated mRNA decay and translational repression. Evidence indicates that both passenger and guide strands of short-interfer...

Ghai, H. S., and L. T. Buck. Acute reduction in whole cell conductance in anoxic turtle brain. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R887–R893, 1999.—We tested the effect of anoxia, a ‘‘mimic’’ turtle artificial cerebrospinal fluid (aCSF) consisting of high Ca21 and Mg21 concentrations and low pH and adenosine perfusions, on whole cell conductance (Gw) in turtle brain ...