Developing seedlings of Catharanthus roseus were analyzed for appearance of tryptophan decarboxylase (TDC), strictosidine synthase (SS), N-methyltransferase (NMT) and O-acetyltransferase (DAT) enzyme activities. SS enzyme activity appeared early after germination and was present throughout most of the developmental study. TDC activity was highly regulated and peaked over a 48 hour period achiev...

Transcriptional corepressors of the Groucho/transducin-like Enhancer of split (Gro/TLE) family are involved in a variety of cell differentiation mechanisms in both invertebrates and vertebrates. They become recruited to specific promoter regions by forming complexes with a number of different DNA-binding proteins thereby contributing to the regulation of multiple genes. To understand how the fu...

Anaerobic expression of the tdcABC operon in Escherichia coli, as measured by LacZ activity from single-copy tdc-lacZ transcriptional and translational fusions, is greatly reduced in strains lacking two global transcriptional regulators, Fnr and ArcA. The nucleotide sequence of the tdc promoter around -145 shows significant similarity with the consensus Fnr-binding site; however, extensive base...

The present study describes and examines the Gro (eloping marriage) in the village of Gro, Kalat. The method was Grounded Theory and the techniques were deep interviews and participant observation. Population under study is young boys and girls who escaped together to marry in the village of Gro, Kalat. In this research purposive or theoretical sampling was used. For better and deeper understan...

An unselected series of 93 Swedish diplegic children born in 1969-1976 and subgrouped into 49 term (TDC) and 44 preterm (PDC) cases were analyzed for differences in reduced optimality in pre- and perinatal conditions, these also being related to degree of handicap, associated neurology and conventional pathogenetic grouping. Comparisons of the reduced optimality with those of a dyskinetic and a...

BACKGROUND Treatment duration varies with the type of therapy and a patient's recovery speed. Including such a variation in randomized controlled trials (RCTs) enables comparison of the actual therapeutic potential of different therapies in clinical care. An index, Treatment Duration Control (TDC) of outcome scores was developed to help decide when to end treatment and also to determine treatme...

The question as to whether or not cancer patients have "tumor antigen"-induced suppressor T cells is of considerable interest and importance. As an approach to that question, the effect of addition of autologous irradiated tumor-derived cells (TDC) on the mixed lymphocyte response (MLR) of patients' lymphocytes (Ly) and of healthy donor Ly was tested. The rationale for these experiments was bas...

A 12-bit Vernier ring time-to-digital converter (TDC) with time resolution of 8 ps for digital-phase-locked-loops (DPLL) is presented. This novel Vernier ring TDC places the Vernier delay cells and arbiters in a ring format and reuses them for the measurement of the input time interval. The proposed TDC thus achieves large detectable range, fine time resolution, small die size and low power con...

Recent studies have shown that exposure to the aroma of ginger root oil (Zingiber officinale Roscoe; termed GRO hereafter) increases the mating competitiveness of males of the Mediterranean fruit fly (medfly), Ceratitis capitata (Wiedemann). This result suggests that pre-release exposure of sterile males to GRO might increase the effectiveness of the Sterile Insect Technique (SIT) against this ...