The concept of support is central to data mining. While the definition of support in transaction databases is intuitive and simple, that is not the case in graph datasets and databases. Most mining algorithms require the support of a pattern to be no grater than that of its subpatterns, a property called anti-monotonicity or admissibility. This study examines the requirements for admissibility ...

Thalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early laboratory tests in rodent populations showed that pregnant rodents could safely use it, so doctors prescribed Thalidomide to treat morning sickness in pregnant women. However, in humans [3] Thalidomide interfered with embryonic and fetal developm...

In the present work, Bilayered matrix type tablet were prepared by direct and wet granulation technique, in which immediate release layer ( compression) contains Nebivolol extended (by granulation) Nateglinide. All developed bilayer tablets evaluated for weight variation, friability, thickness hardness. The percent deviation from average weight, hardness was found to be within prescribed offici...

A novel, sensitive, stability indicating RP-HPLC method has been developed for the quantitative estimation of Metformin Hydrochloride impurities in both bulk drugs and pharmaceutical dosage forms. Effective chromatographic separation was achieved on a C8 stationary phase with simple mobile phase combination delivered in a isocratic mode and quantitation was by ultraviolet detection at 218 nm. T...

Psoriasis is a chronic inflammatory disease that directly affects the quality of life. Biologics are prescribed for patients unresponsive to conventional treatments and with severe forms of the disease. Ustekinumab is a fully human monoclonal antibody against the p40 subunit of interleukins 12/23 that is being used with satisfactory responses, achieving an improvement in the baseline Psoriasis ...

Thalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early laboratory tests in rodent populations showed that pregnant rodents could safely use it, so doctors prescribed Thalidomide to treat morning sickness in pregnant women. However, in humans [3] Thalidomide interfered with embryonic and fetal developm...

The physico-chemical characteristics of methanogenic granules are one of the most important properties for the successful operation of upflow anaerobic sludge blanket, since they could directly affect the substrate and nutrient transportation into granules. In this study, the effect of low strength ultrasonication on the settling velocity, permeability, porosity, and fluid collection efficiency...

Thalidomide is a sedative drug introduced to European markets on 1 October 1957 after extensive testing on rodent embryos to ensure its safety. Early laboratory tests in rodent populations showed that pregnant rodents could safely use it, so doctors prescribed Thalidomide to treat morning sickness in pregnant women. However, in humans [3] Thalidomide interfered with embryonic and fetal developm...

Background: Refractive error is defined as a status of refraction. They happen when the shape your eye keeps light from focusing correctly on retina (a light-sensitive layer tissue in back eye). errors are most common type vision problem but many don’t know that they could be seeing well.Methods: This study was cross sectional hospital-based 197 children carried out ophthalmology department Era...