The conserved coat protein complex II (COPII) mediates the initial steps of secretory protein trafficking by assembling onto subdomains of the endoplasmic reticulum (ER) in two layers to generate cargo-laden transport carriers that ultimately fuse with an adjacent ER-Golgi intermediate compartment (ERGIC). Here, we demonstrate that Trk-fused gene (TFG) binds directly to the inner layer of the C...

Trigonella foenum-graecum (Fabaceae) is a medicinal plant. It is traditionally used in the treatment and prevention of several ailments. Pharmacological investigations showed anti-bacterial, anti-diabetic, anticancer, anti-diarrheal, anti-inflammatory activities. Phytochemical analysis showed the presence of quinone, flavones, flavonoids, phenols, tannins, terpenoids, lactones, alkaloids and po...

Methanol extracts from 27 medicinal plant species were tested at concentrations of 0.5, 1 and 2 mg/mL for their in vivo fungicidal activities against six phytopathogenic fungi. Their efficacy varied with plant pathogen, tissue sampled and plant species. Very strong fungicidal activity was produced by extracts of Boswellia carterii, Saussurea lappa, Glycyrrhiza uralensis, Piper nigrum, Rheum cor...

Thiosemicarbazides have found to contain antimicrobial, antiviral activities against various virus, bacteria and fungi strains. The objective of the study was to study the seed germination and physiological maturity stage of Trigonella foenum graecum and Brassica (L.). The effect of various concentrations of 1γ picolinoyl-4-phenyl Thiosemicarbazides on mitotic Indices in root tip cell in Trigon...

PURPOSE Despite innumerous both therapeutic and histopathologic studies that have been performed no morphologic markers are currently available in order to predict the outcome in patients with laryngeal cancer. According to the recent reports nowadays tumor front grading (TFG) is one of the most reliable methods of estimation of the progress of the changes in the peripheral part of tumor and it...

There is a growing awareness in the multiagent systems research community that the environment plays a prominent role in multiagent systems. Originating from research on behavior-based agent systems and situated multiagent systems, the importance of the environment in multiagent systems is now gradually accepted in the multiagent system community in general. The aim of the AgentLink Technical F...

The TRK-fused gene (TFG) was originally identified in chromosome translocation events, creating a pair of oncogenes in some cancers, and was recently demonstrated as the causal gene of hereditary motor and sensory neuropathy with proximal dominant involvement. Recently, we cloned an alternative splicing variant of Tfg from a cDNA library of the rat retina, tentatively naming it retinal Tfg (rTf...

This study was undertaken to examine the antioxidant activity of methanolic extract of seeds of Trigonella foenum-graecum seeds using DPPH free radical scavenging assay. The IC50 (The concentration of sample required to scavenge 50% of DPPH free radical) was calculated by plotting graph between % inhibition vs concentration. The Ascorbic acid was used as standard antioxidant in comparison to me...

Diabetes is an oxidative stress disorder and oxidative damage to tissues such as heart, kidney, liver and other organs may be a contributory factor to several diabetic complications. Momordica charantia (family: Cucurbitaceae) and Trigonella foenum graecum (family: Fabaceae) are used traditionally in Indian folk medicine to manage diabetes mellitus. In the present study, the anti-hyperglycemic ...