Surgical ovarian wedge resection was the first established treatment for women with anovulatory polycystic ovary syndrome (PCOS) but was largely abandoned both due to the risk of postsurgical adhesions and the introduction of medical ovulation induction. Laparoscopic ovarian drilling (LOD) is an alternative method to induce ovulation in PCOS patients with clomiphene citrate resistance instead o...

In this study, we investigated effects of Anacyclus pyrethrum L. aqueous root extracts on gonadotropins (LH, FSH) and testosterone serum in adult male rats. A total number of 60 male adult rats were divided randomly into five groups (n=12) including one control group (A), sham control (B) and three test groups (C, D and E). Test groups (C, D and E) received 50, 100, 150 mg/kg does of A. pyrethr...

Several case reports have indicated that a small subgroup of patients may develop ovarian hyperstimulation following the administration of gonadotropin-releasing hormone agonists (GnRHa) without gonadotropins. However, since only few such cases have been published, it is unclear what course to follow in subsequent cycles after ovarian hyperstimulation in the first cycle using only GnRHa. A 33-y...

There are a few studies about the secretion of gonadotropins in women. Acute testosterone infusion to normal women with and without testolactone inhibits LH sssecretion in a dose-dependent manner, without no effect on FSH secretion, while short-term administration of testosterone to normal women and eugonadal female-to-male transsexuals did not alter either gonadotropin levels, or affect the pu...

The aim of the study was to compare the effectiveness of stimulation of gilts puberty by natural method and with gonadotropins. The results of reproduction parameters of gilts were also compared. Gilts were also supported by diet with easilly assimilated carbohydrates. The study was carried out on the group of 80 gilts which were divided into 2 groups (A and B) according to the method of induci...

A comparison of the amino acid sequences demonstrated that Siberian tiger gonadotropins are more homologous with those of porcine than any other commercially available preparation. The present study measured the efficacy of repeated ovarian stimulation with purified porcine gonadotropins on the follicular, hormonal, and immunogenic responses in Siberian tigers as well as on the ability of oocyt...

Radioiodinated human FSH (‘?-hFSH) was used to study the specificity of the gonadotropin binding sites of various reptilian, avian, and mammalian gonadal tissues by examining competitive interactions with several nonmammalian gonadotropins. All preparations of nonmammalian gonadotropins showed some activity in these radioligand assays, but wide variations in activities were evident depending on...

Expression of pituitary adenylate cyclase-activating polypeptide (PACAP), a neuropeptide with considerable homology to vasoactive intestinal peptide, has been shown to be stimulated by gonadotropins in the ovary. The present studies further evaluated the cell-type specific expression and gonadotropin regulation of PACAP type I receptor (PACAPR) messenger RNA in immature rat ovaries and in cultu...

This exceptionally well done book organizes the proceedings of the International Symposium on Gonadotropins held at the New York Hospital Bicentennial Celebration in 1971 into 58 essays which survey the chemistry and physiology of FSH, LH, and prolactin. The book's major attribute is the special care taken to present gonadotropin research in perspective. Thus, the first essay, if not all of the...