Gorlin-Goltz syndrome (GGS) among Indians is rarely reported. Since 1960, only 38 cases having 48 patients of have been identified in the Indian population. It crucial to diagnose this illness early because it can be connected a malignant lesion like fibrosarcoma, leiomyosarcoma or rhabdomyosarcoma. The four case series were and treated our department between 2019 2023. average patient age was ...

The Gulf Journal of Dermatology and Venereology ABSTRACT Focal dermal hypoplasia (FDH) or Goltz syndrome is a rare genodermatosis, characterized by multiple abnormalities of ectodermal and mesodermal origin. We present an infant with focal dermal hypoplasia who, besides having a constellation of anomalies commonly encountered in patients with this syndrome, manifested additional unusual feature...

Address for correspondence: Prof. Henryk Witmanowski MD, PhD, Department of Plastic, Reconstructive and Aesthetic Surgery, Medical College, Nicolaus Copernicus University, 9-11 M. Skłodowska-Curie St, 85-094 Bydgoszcz, phone: +48 52 585 4017, email: [email protected] Received: 21.06.2016, accepted: 2.08.2016. Basal cell nevus syndrome (Gorlin-Goltz syndrome): genetic predisposition, clinical picture...

Gorlin-Goltz syndrome, also known as nevoid basal cell carcicoma syndrome, comes into being due to a genetic alteration produced by a mutation in the "Patched" tumour suppressor gene, and it is inherited in a dominant autosomal way, though sporadic cases have been found. This syndrome shows a high penetrance and variable expressiveness. It is about a multisystemic process that is characterised ...

Basaloid follicular hamartoma (BFH) is a rare and benign adnexal tumor that resembles basal cell carcinoma (BCC) may present with different clinical manifestations. A mutation in the PTCH gene, involved Gorlin-Goltz syndrome, could be associated pathogenesis of this neoplasm. We describe case 7-year-old girl multiple papules on her face.

ACTA DERMATOVENEROLOGICA CROATICA The Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma (BCC), has a variable prevalence, estimated from 1/57,000 to 1:256,000 inhabitants (1). It is a rare autosomal dominant disorder due to a genetic mutation in the PTCH tumor suppressor gene localized to 9q22.3 chromosome (2). In order to make a diagnosis of Gorlin-Goltz syndrome, some diagnosti...

Focal dermal hypoplasia or Goltz syndrome is a rare X-linked genodermatosis characterized by cutaneous and musculoskeletal defects. Dermoscopy is a noninvasive auxiliary method for the diagnosis of lesions, whether melanocytic or not. Its widespread use in dermatology is resulting in the description of new patterns and characterization of lesions not reported before its use. A typical case of G...