Multinodular goitre is the most prevalent thyroid pathological abnormality worldwide, although its geographical incidence varies greatly according to environmental iodization Most countries in central and southern Europe have endemic goitre areas with a prevalence of multinodular goitre (MG) of 3-6%. In United States, the annual incidence of nodular thyroid disease is 0.1% to 1.5% and the preva...

The Medical Journal of Australia ISSN: 0025729X 4/18 December 2006 185 11/12 677-677 ©The Medical Journal of Australia 2006 www.mja.com.au Christmas Offerings in Nilgiri rhesus monkeys is the result of low iodine mountain environment. Further investigation is necessa the exact reason for the goitre. A literature search failed to identify any studies of end humans living in the Nilgiri region, a...

Nutritional iodine deficiency and endemic goitre are widely prevalent in India. Surveys conducted by the National Goitre Control programme showed high prevalence areas of endemic goitre in 75 of the 88 districts.in 14 states of India. A more recent country-wide survey for extra-Himalayan foci of endemic goitre revealed prevalence of goitre in all the 14 districts studied.' In all investigations...

We present the case of a thirty-year-old female patient who was referred to the endocrinology team with an enlarging goitre and biochemical hypothyroidism. She had been dependent on total parenteral nutrition for the previous six years as a result of intestinal failure thought to be caused by possible underlying mitochondrial disease. The patient also suffers from a Desmin myopathy, and at pres...

The prevalence of endemic goitre is extremely high in certain parts of Sri Lanka where rates as high as 44% have been observed. With nearly 10 million people at risk the aetiology of endemic goitre in Sri Lanka needs to be clearly ascertained. The endemic goitre belt of Sri Lanka coincides with the wet climatic zone, indicating an apparent relationship of iodine geochemistry with climatic facto...

Iodine is an essential micronutrient for human health. Its deficiency causes a number of functional and developmental abnormalities such as goitre. The limestone region of Derbyshire, UK was goitre-endemic until it declined from the 1930s and the reason for this has escaped a conclusive explanation. The present study investigates the cause(s) of goitre in the UK-Peak District area through an as...

In the absence of maternal thyroid disease or iodine deficiency, fetal goitre is rare and usually attributable to dyshormonogenesis, for which genetic ascertainment is not always undertaken in the UK. Mechanical complications include tracheal and oesophageal compression with resultant polyhydramnios, malpresentation at delivery and neonatal respiratory distress. We report an Indian kindred in w...

In the present review paper, the following problems have been brought up: 1) types of non-toxic goitre and applied classifi cation, 2) physiological periods or states predisposing to non-toxic goitre develop-

Goitre has been declining in Italy since the 1970s and because active prophylaxis (AP) has been very limited, it has been suggested that in most places the decline was due to silent prophylaxis (SP). SP is related to the natural increase in iodine intake because of higher consumption of iodine-rich products associated with socioeconomic development. The hypothesis tested in the present study is...

Sir Robert McCarrison's work on goitre, cretinism and the thyroid, begun in the western Himalayas in 1902, generated scores of scientific publications during the following thirtyfive years.1 Though that work is often considered the start of serious studies of goitre and cretinism in South Asia, in fact the use of iodine in goitre treatment in this region was noted by Commissioner David Scott at...