BACKGROUND Complications increase treatment costs of diabetes mellitus (DM). An adequate metabolic control of the disease could reduce these costs. AIM To evaluate the costs of medical care for a cohort of patients with DM, according to their degree of metabolic compensation. MATERIAL AND METHODS All diabetic patients attended in a regional hospital from 2005 to 2010 were analyzed. A correl...

Glycation is the nonenzymatic addition of sugar to amino groups of proteins. While virtually any protein in the body can be glycated, for convenience and ease of obtaining a sample, glycated hemoglobin is measured in the blood obtained from a patient. Blood glucose concentrations exhibit wide diurnal fluctuations due to food ingestion, exercise, and other factors. In contrast, the concentration...

OBJECTIVE The goal of this study was to describe medication usage patterns in patients with type 2 diabetes mellitus (T2DM) initiating treatment with non-insulin antidiabetic drugs (NIADs), basal insulin, or prandial/mixed insulin using real-world data. RESEARCH DESIGN AND METHODS A retrospective analysis using the Truven Health MarketScan Research Databases was conducted to identify adults (...

OBJECTIVE To investigate whether socioeconomic status and psychological well-being (eudaimonic and hedonic aspects) predicted nondiabetic levels of glycosylated hemoglobin (HbA1c) over time, after adjusting for covariates and baseline level of HbA1c. METHODS These questions were investigated with a longitudinal sample (n = 97; age = 61-91 years) of older women without diabetes. Socioeconomic ...

OBJECTIVE Characterize the impact of a pharmacist-led diabetes self-management program on three key metabolic parameters: glycosylated hemoglobin (HbA1c), low-density lipoprotein cholesterol (LDL-C), and mean arterial blood pressure (MAP) among employee health program participants. METHODS A self-insured company in the Kansas City metropolitan area began offering a pharmacist-led diabetes sel...

OBJECTIVES A study was made of the effect of nonsurgical periodontal treatment upon blood glucose control in type 2 diabetics with periodontal disease. STUDY DESIGN A pre-post repeated measures analytical design was used, with a PubMed search of the related articles published up until December 2008. RESULTS The improvement in glycosylated hemoglobin (HbA1c) after nonsurgical periodontal tre...

Partially purified hemoglobin A2 has been examined for the existence of glycosylated components by isoelectric focusing and by acid agar gel electrophoresis. Bands analogous to the glycohemoglobin derivatives of hemoglobin A, hemoglobin-A1.a.b.c, were readily detected. Evidence that these minor bands are in fact glycohemoglobins was obtained by showing that 14C-glucose bound to hemoglobin A2 mo...

Mothers who have big babies may have had abnormal glucose tolerance during pregnancy. Glycosylated haemoglobin (HbA1) concentrations were measured on the first or second day after delivery in 50 women who had had babies weighing over the 95th centile for gestational age and in 50 women who had had normal-sized babies (controls). Nine of the mothers of big babies but only one of the controls had...

The importance of education in the management of diabetes is recognised but has rarely been assessed in children. In a longitudinal controlled study we have examined the effect of a programme of education on the knowledge, diet, and concentration of glycated haemoglobin A1c in a group of diabetics. The programme took the form of two packages of education each consisting of four weekly meetings,...

Serum fructosamine and glycated haemoglobin (HbA1) were measured in capillary samples from diabetic children and compared with samples from non-diabetic children. Glycaemic control was assessed clinically and by average daily glucose values recorded by home monitoring. Fructosamine correlated with HbA1 and with average glucose values measured over 30 days. HbA1 also correlated with average gluc...