1. A phosphodiesterase that cleaves glycerophosphoinositol into glycerophosphate and inositol has been detected in rat tissues. 2. The enzyme requires Mg2+(Mn2+) and has a pH optimum of 7.7. 3. The richest sources of the enzyme are kidney and intestinal mucosa. In pancreas subcellular fractions it occurs largely in the microsomal fraction. 4. The enzyme is inhibited by excess substrate and by t...

An antigen composed of glycerophosphate and glucose has been isolated from the cell walls of a strain of Staphylococcus albus. The antigen reacted with homologous and heterologous S. albus antisera. Similar material was isolated from the cell walls of three other S. albus strains. The antigen did not react with S. aureus antiserum nor with normal human or rabbit serum. The antigen appeared to h...

Activities of the enzymes monoamine oxidase (EC 1.4.3.4), alpha-glycerophosphate dehydrogenase (EC 1.1.99.5) and cytochrome oxidase (EC 1.9.3.1) were determined in homogenates and in the mitochondrial fraction prepared from individual regions of pig brain. The variation in the activity of alpha-glycerophosphate dehydrogenase paralleled that of cytochrome oxidase, but this was not the case with ...

1. The kinetics of the reaction of glycerophosphate dehydrogenase with a variety of electron acceptors have been investigated. 2. In all cases the reaction mechanism appears to involve a free modified-enzyme intermediate. 3. With some electron acceptors, the maximum velocity of the reaction and the K(m) for glycerophosphate are independent of the nature of the electron acceptor, whereas in othe...

background: the efficacy of fluoridated dentifrices in caries prevention has been well documented and research into various formulations continues for a more effective dentifrice. this study evaluated the anti-caries and anti-plaque efficacy of a dentifrice containing sodium monofluorophosphate (1000 ppm) and calcium glycerophosphate, and compared it with a non-fluoridated dentifrice. materials...

OBJECTIVE Vascular calcification is highly correlated with increased cardiovascular morbidity and mortality. C1q/tumor necrosis factor-related protein-3 (CTRP3) is a newly identified adipokine that plays important roles in cardiovascular system. Here, we investigated the role of CTRP3 in vascular calcification and its underlying mechanism. APPROACH AND RESULTS Adenine-induced chronic renal fa...

The distribution and localization-pattern of certain DPN-linked dehydrogenases (malic, lactic, D-glucose, glutamic, and a-glycerophosphate) were demonstrated histochemically in the red and white fibres of pigeon breast-muscle by using neotetrazolium as the hydrogen acceptor, under strictly anaerobic conditions. All the dehydrogenases studied showed distinctly higher enzyme activity in the narro...