نتایج جستجو برای: glutamic acid decarboxylase
تعداد نتایج: 753728 فیلتر نتایج به سال:
Stiff-person syndrome is an autoimmune syndrome defined by muscle spasms and rigidity of proximal and axial muscles. Glutamic acid decarboxylase is the autoantigen found in 60%–80% of stiff person syndrome patients. Stiff person syndrome, cerebellar variant was characterized in a subpopulation of patients (5 of 38) with stiff person syndrome and concomitant cerebellar dysfunction and confirmed ...
Gamma‐aminobutyric acid (GABA) possibly plays a causative role in mood disorders. This hypothesis originated with studies on the beneficial effect of valproate in mania and as a mood stabilizer. Since valproate is known for its action in increasing the level of GABA, it was indirectly suggested that decreasing levels of GABA were responsible for mood alterations. To identify factors causing the...
An Eighty-three-year-old woman diagnosed with slowly progressive insulin-dependent (type 1) diabetes mellitus due to high serum level of anti-glutamic acid decarboxylase antibody underwent coronary artery bypass grafting. She had abdominal pain and died 5 days after the operation. At autopsy, we found dissection of the right coronary artery, acute myocardial ischemia at the posterior septal wal...
IMPORTANCE Stiff person syndrome (SPS) is a rare neurological disease causing significant functional disability for patients and presenting a therapeutic challenge for clinicians. Autologous hematopoietic stem cell transplantation (auto-HSCT) has been used successfully to remit autoimmune-mediated neurological diseases. We report 2 cases of severe SPS treated with auto-HSCT, a novel therapy for...
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