Objective: Stress and cortisol increase blood glucose. Considering the role of central catecholaminergic pathways on hypothalamic-pituitary adrenocortical axis, and results of some studies that alprazolam (a benzodiazepine) has inhibitory effect on catecholamines, it seems that alprazolam may reduce blood glucose. The aim of this study was to evaluate the effect of alprazolam on serum insulin l...

objective: type 2 diabetes (t2d) as a complex disease is the result of genetically heterogeneous factors and environmental issues interaction. linkage and small-scale candidate gene studies were successful in identification of genetic susceptibilities of monogenic form of diseases. however, they were largely unsuccessful while applying to the more common forms of disease. by designing genome wi...

background: saffron is the dried stigmata of the flowers of saffron (crocus sativus l., iridaceae). saffron and its major active constituents, crocin (crocetin glycoside), crocetin and safranal, have a variety of pharmacological effects including high antioxidant properties and crocetin has insulin sensitizing effect possibly due to its antioxidant activity. oral crocin is not absorbed and is h...

hyperglycemia and gestational diabetes mellitus are complications of pregnancy. both mothers and newborns are typically at increased risk for complications. this study sought to determine effect of zinc supplementation on serum glucose levels, insulin resistance, energy and macronutrients intakes in pregnant women with impaired glucose tolerance.in this clinical trial 44 pregnant women with imp...

OBJECTIVE: Hyperglycemia is associated with increased morbidity and mortality in diabetic patients following coronary artery bypass grafting. Tight glycemic control in perioperative period can reduce these events. The goal of this study was to determine whether combination of continuous infusion and subcutaneous glargine as a basal insulin could improve glycemic control. MATERIAL AND METHODS:...

indian traditional system of medicine has been used plants and herbs for treatment of diabetes since time of vedic glory. in this regard many plants still untouched, having remarkable efficacy. the blood sugar lowering effect of 95% ethanolic extract of c. tamala ( hamm.) nees. & eberm., leaves was investigated at single oral dose of 250mg/kg body weight in normal fasted, fed, glucose loaded an...

b a ckground: diabetes is an important disease. this disease is a metabolic disorder characterized by hyperglycemia resulting from perturbation in insulin secretion, insulin action or both. honey bee venom contains a wide range of polypeptide agents. the principle components of bee venom are mellitin and phospholipase a2. these components increase insulin secretion from the β-cells of pancreas....

Abstract Diabetes mellitus is a metabolic disease characterized by hyperglycemia resulting from either defect in insulin secretion, insulin action, or both. Postprandial hyperglycemia is a prime characteristic of diabetes mellitus and has been a focus in the therapy for diabetes. One of the therapeutic approaches which involve decreasing hyperglycemia aims at lowering blood glucose...

objective(s):in insulin resistance, the insulin action in liver, muscles and adipocytes decreases and result in hyperglycemia, dyslipidemia and hyperinsulinemia. in this study we evaluate the effect of zataria multiflora extract on insulin sensitivity in high fructose fed insulin resistant rats, since this extract was shown antihyperglycemic effect in streptozotocin induced diabetes in rats.   ...

Background: Diabetes mellitus (DM) is a common chronic disease with diverse complications. About 10% of the earth's population suffer from this disease. For smart control of the blood glucose in DM patients, an artificial pancreas was designed and simulated by a predictive sliding mode controller considering the time delay of insulin effect. Method: In this method, one of the time-delay glucos...