Glucosinolates, phytochemicals found in cruciferous vegetables, are metabolised to bioactive isothiocyanates (ITC) by certain bacteria in the human gut. Substantial individual variation in urinary ITC excretion has been observed in previous cruciferous vegetable-feeding studies. We hypothesised that individual differences in gut microbial community contribute to the observed variation in glucos...

Broccoli sprouts are a convenient and rich source of the glucosinolate, glucoraphanin, which can generate the chemopreventive agent, sulforaphane, an inducer of glutathione S-transferases (GST) and other cytoprotective enzymes. A broccoli sprout-derived beverage providing daily doses of 600 μmol glucoraphanin and 40 μmol sulforaphane was evaluated for magnitude and duration of pharmacodynamic a...

Sulforaphane (SFN) is an isothiocyanate which is produced through glucoraphanin hydrolysis via myrosinase activity. In the present study, SFN content and peroxidase activity has been assessed in treated Lepidium draba seedlings with different concentrations of iron and copper during 8 and 16 hours treatment. The results showed that the SFN content drastically elevated at treatment with...

sulforaphane (sfn) is an isothiocyanate which is produced through glucoraphanin hydrolysis via myrosinase activity. in the present study, sfn content and peroxidase activity has been assessed in treated lepidium draba seedlings with different concentrations of iron and copper during 8 and 16 hours treatment. the results showed that the sfn content drastically elevated at treatment with 1 mg/l f...