ABSTRACT In this issue of Clinical Kidney Journal, Stehlé and colleagues demonstrate that estimation glomerular filtration rate (GFR) by use creatinine a measure, total lumbar muscle cross-sectional area, reflecting the mass an individual, is superior to GFR-estimating equations based upon demographic variables. The report et al. demonstrates one solution interference in estimate GFR. This was ...

We evaluated the glomerular filtration rate (GFR) during the second postpartum week in 22 healthy women who had completed an uncomplicated pregnancy. We used physiological techniques to measure GFR, renal plasma flow, and oncotic pressure and computed a value for the two-kidney ultrafiltration coefficient (K(f)). We compared these findings with those in pregnant women previously studied on the ...

Drug-dose modification in chronic kidney disease (CKD) utilizes glomerular filtration rate (GFR) with the implicit assumption that multiple renal excretory processes decline in parallel as CKD progresses. We compiled published pharmacokinetic data to evaluate if GFR predicts renal clearance changes as a function of CKD severity. For each drug, we calculated ratio of renal clearance to filtratio...

Introduction: We intended to assess the accuracy of re-expressed Modification of Diet for Renal Disease (MDRD) and Cockcroft-Gault (CG) equations to estimate glomerular filtration rate (GFR) in chronic kidney disease in two different etiologies of acute renal failure (ARF): acute tubular necrosis (ATN) and acute glomerulonephritis (AGN). Methods: Patients admitted for ARF or the patients compl...

Objective: Chronic kidney disease (CKD) and diabetes mellitus can influence coronary artery disease (CAD) independently. The aim of this study was to evaluate the association of glomerular filtration rate (GFR) and CAD in type 2 diabetic patients (T2DM). Materials and Methods: This cross sectional study evaluated 3624 T2DM patients with clinical presentation of CAD whose documents were registe...

Glomerular filtration rate (GFR) and renal blood flow (RBF) are normally kept constant via renal autoregulation. However, early diabetes results in increased GFR and the potential mechanisms are debated. Tubuloglomerular feedback (TGF) inactivation, with concomitantly increased RBF, is proposed but challenged by the finding of glomerular hyperfiltration in diabetic adenosine A(1) receptor-defic...

Diabetes is the main cause for diabetic kidney disease (dkd), which affects filtering units of kidneys slowly and stops it’s function finally. This consequence common both genetic based (type 1) lifestyle 2) diabetes. However, type 2 diabetes plays a significant influence in increased urine albumin excretion, decreased glomerular filtration rate (gfr), or both. These causes failure stage by sta...

● Kidney damage for 3 months, as defined by structural or functional abnormalities of kidney, with or without decreased glomerular filtration rate (GFR), manifest by either: Pathological abnormalities Markers of kidney damage, including abnormalities in composition of blood or urine, or abnormalities in imaging tests ● GFR 60 mL/min/1.73 m ( 1.00 mL/s) for 3 months, with or without kidney damag...

Multiphoton fluorescence microscopy offers the advantages of deep optical sectioning of living tissue with minimal phototoxicity and high optical resolution. More importantly, dynamic processes and multiple functions of an intact organ can be visualized in real time using noninvasive methods, and quantified. These studies aimed to extend existing methods of multiphoton fluorescence imaging to d...