نتایج جستجو برای: gib usbl sbl lbl

تعداد نتایج: 1720  

2017
Ka-Shing Cheung Wai K Leung

Novel oral anticoagulants (NOACs), which include direct thrombin inhibitor (dabigatran) and direct factor Xa inhibitors (rivaroxaban, apixaban and edoxaban), are gaining popularity in the prevention of embolic stroke in non-valvular atrial fibrillation as well as in the prevention and treatment of venous thromboembolism. However, similar to traditional anticoagulants, NOACs have the side effect...

2013
Jean-Marc Regimbeau David Fuks Emilie Chapuis-Roux Thierry Yzet Cyril Cosse Eric Bartoli Eric N'Guyen-Khac Brice Robert Eric Lobjoie

The preoperative management of hilar cholangiocarcinoma (HC) with jaundice focuses on decreasing the total serum bilirubin level (SBL) by performing preoperative biliary drainage (PBD). However, it takes about 6-8 weeks for the SBL to fall at a sufficient extent. The objective of this preliminary study was to evaluate the impact of Molecular Adsorbent Recirculating System (MARS(®)) dialysis (in...

Journal: :Physical review letters 2017
Myoung-Gyun Suh Qi-Fan Yang Kerry J Vahala

Laser linewidth is of central importance in spectroscopy, frequency metrology, and all applications of lasers requiring high coherence. It is also of fundamental importance, because the Schawlow-Townes laser linewidth limit is of quantum origin. Recently, a theory of stimulated Brillouin laser (SBL) linewidth has been reported. While the SBL linewidth formula exhibits power and optical Q factor...

2017
Shuanghui Zhang Yongxiang Liu Xiang Li

Interferometric inverse synthetic aperture radar (InISAR) imaging for sparse-aperture (SA) data is still a challenge, because the similarity and matched degree between ISAR images from different channels are destroyed by the SA data. To deal with this problem, this paper proposes a novel SA-InISAR imaging method, which jointly reconstructs 2-dimensional (2-D) ISAR images from different channels...

2014
TAKEO TATSUTA MASAHIRO HOSONO YUKIKO OGAWA KYOKO INAGE SHIGEKI SUGAWARA KAZUO NITTA

Heat shock proteins (Hsps) are molecular chaperones that maintain homeostasis of organisms. In regards to the Hsps, many studies have investigated the structure, expression, localization and functions of Hsp70 and Hsc70 including expression in the glycosphingolipid-enriched microdomain (GEM) on the cell surface and involvement in cell death. Sialic acid-binding lectin (SBL) isolated from oocyte...

2013
TAKEO TATSUTA MASAHIRO HOSONO YUKI MIURA SHIGEKI SUGAWARA YUKIKO KARIYA SENITIROH HAKOMORI KAZUO NITTA

Sialic-acid binding lectin (SBL) isolated from bullfrog (Rana catesbeiana) oocytes is a multifunctional protein which has lectin activity, ribonuclease activity and cancer-selective antitumor activity. It has been reported that SBL induces apoptosis accompanied by rigid mitochondrial perturbation, which indicates mediation of the intrinsic pathway. However, the mechanism of the antitumor effect...

Journal: :Cancer research 1994
K Nitta K Ozaki Y Tsukamoto S Furusawa Y Ohkubo H Takimoto R Murata M Hosono N Hikichi K Sasaki

Sialic acid-binding lectin (SBL-C) from Rana catesbeiana eggs inhibits the growth of tumor cells such as P388 and L1210 leukemia cells (K. Nitta et al., Cancer Res., 54: 920-927, 1994). Here we report the establishment of an SBL-resistant P388 variant cell line, RC-150. Both P388 and RC-150 cells were agglutinated by SBL-C; however, growth of RC-150 cells was unaffected by SBL-C. Cytoplasmic fr...

2010
N. Hari Narayanan Dean Hendrix Lakshman Myneni Margaret Ross

Studio-Based Learning (SBL) is a novel learner-centered and collaborative learning model for computing education. This model has been under development and evaluation in computing courses at three universities (Auburn, Washington State and Hawaii) with support from the National Science Foundation. Adapted from architecture and art education, as well as from collaborative problem-solving pedagog...

2014
TAKEO TATSUTA MASAHIRO HOSONO KOHTA TAKAHASHI TAKASHI OMOTO YUKIKO KARIYA SHIGEKI SUGAWARA SENITIROH HAKOMORI KAZUO NITTA

Malignant mesothelioma is a highly aggressive tumor with poor prognosis. An effective drug for treatment of malignant mesothelioma is greatly needed. Sialic acid-binding lectin (SBL) isolated from oocytes of Rana catesbeiana is a multifunctional protein which has lectin activity, ribonuclease activity and antitumor activity, so it could be developed as a new type of anticancer drug. The validit...

2017
Thomas M Attard Mikaela Miller Chaitanya Pant Ashwath Kumar Mike Thomson

AIM To determine the clinical characteristics of children with gastrointestinal bleeding (GIB) who died during the course of their admission. METHODS We interrogated the Pediatric Hospital Information System database, including International Classification of Diseases, Current Procedural Terminology and Clinical Transaction Classification coding from 47 pediatric tertiary centers extracting t...

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