Giant cell arteritis is a granulomatous vasculitis of large and medium sized arteries manifesting as temporal arteritis and/or polymyalgia rheumatica. The histological assessment of temporal artery biopsies is frequently encountered in anatomical pathology and has important diagnostic consequences in patients clinically suspected of having giant cell arteritis. We present an intriguing case of ...

DESCRIPTION A 60-year-old woman presented with a 15 × 15-cm fungating tumor of the posterior scalp.

A 64-year-old man, phototype V in Fitzpatrick scale, presented with a 5-year history of a slowly extending ulcer of the scalp. He had a past medical history of diabetes mellitus and ionizing radiation for tinea capitis in childhood. The physical examination revealed an oval-shaped ulcer measuring 7 cm in width x 5 cm in length, with a raised pigmented border; the center was alopecic, scattered ...

Abstract Basal cell carcinoma (BCC) is the most common skin cancer. However, BCC on scrotum very rare, with an incidence of 0.03%. Giant BCC, in which tumour larger than 5 cm, has also been reported as a rare variant. Here, we report 71‐year‐old male giant and review similar cases English. None four scrotum, including present case, showed lymph node or distant metastasis. Wide local excision wa...

background and objective: clinical behavior of basal cell carcinoma (bcc) is known to be different according to histological growth pattern and basosquamous cell carcinomas (bsc) are known with their aggressive behavior and metastatic capacity. in this study, we evaluated bcl-2 and cyclin d1 expressions in bcc and bsc cases comparatively, to explore their predictive value on the aggressive beha...

Background: The most frequently mutated tumor suppressor gene found in human cancer is p53. In a normal situation, p53 is activated upon the induction of DNA damage to either arrest the cell cycle or to induce apoptosis. However, when mutated, p53 is no longer able to properly accomplish these functions. The aim of this study was to investigate the expression of p53 gene in cases of skin cancer...

nevoid basal cell carcinoma syndrome (nbccs), also known as gorlin syndrome, is a hereditary condition characterized by a wide range of developmental abnormalities and a predisposition to neoplasms . the estimated prevalence varies from 1/57,000 to 1/256,000, with a male-to-female ratio of 1:1. main clinical manifestations include multiple basal cell carcinomas (bccs), odontogenic keratocysts o...

Basal cell carcinoma is a malignant epithelial neoplasm of the skin and most common human cancer. It generally associated with good prognosis. In this case report, giant basal nodulo-ulcerative type showing wide ulceration marginal multiple small nodules, presented. was trapezoidal in shape, having dimensions 7 cm at greatest width, 6 vertically different anterior posterior margin dimensions, 5...