نتایج جستجو برای: gestational exposure

تعداد نتایج: 341170  

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2004
David W Herr Sushmita M Chanda Jaimie E Graff Stanley S Barone Robert P Beliles Daniel L Morgan

Mercury is known to alter neuronal function and has been shown to cross the placental barrier. These experiments were undertaken to examine if gestational exposure to mercury vapor (Hg(0)) would result in alterations in sensory neuronal function in adult offspring. Dams were exposed to 0 or 4 mg/m(3) Hg(0) for 2 h/day from gestational days 6-15. This exposure paradigm has been shown to approxim...

Journal: :American journal of physiology. Lung cellular and molecular physiology 2005
Suhas G Kallapur Ilias Nitsos Timothy J M Moss Boris W Kramer John P Newnham Machiko Ikegami Alan H Jobe

Chronic early gestational chorioamnionitis is associated with development of bronchopulmonary dysplasia in preterm infants. A single intra-amniotic exposure to endotoxin decreased alveolarization and reduced expression of endothelial proteins in 125-day gestational age preterm lambs. We hypothesized that prolonged exposure to intra-amniotic endotoxin would cause progressive lung inflammation an...

2015
María Teresa Ramírez-López Mariam Vázquez Laura Bindila Ermelinda Lomazzo Clementine Hofmann Rosario Noemí Blanco Francisco Alén María Antón Juan Decara Daniel Ouro Laura Orio Juan Suarez Beat Lutz Fernando Rodríguez de Fonseca Raquel Gómez de Heras

Exposure to unbalanced diets during pre-gestational and gestational periods may result in long-term alterations in metabolism and behavior. The contribution of the endocannabinoid system to these long-term adaptive responses is unknown. In the present study, we investigated the impact of female rat exposure to a hypercaloric-hypoproteic palatable diet during pre-gestational, gestational and lac...

Journal: :American journal of epidemiology 2002
Britt Clausson Fredrik Granath Anders Ekbom Stefan Lundgren Anna Nordmark Lisa B Signorello Sven Cnattingius

Epidemiologic studies have been unable to conclusively evaluate whether caffeine intake during pregnancy is associated with reduced birth weight and/or fetal growth restriction. The authors conducted a prospective, population-based cohort study to investigate the effect of caffeine on birth weight, gestational age, and birth weight standardized for gestational age (birth weight ratio). Of 953 w...

2012
Stephen A. Rauch Joe M. Braun Dana Boyd Barr Antonia M. Calafat Jane Khoury M. Angela Montesano Kimberly Yolton Bruce P. Lanphear

BACKGROUND Prenatal exposure to organophosphate (OP) insecticides, a widely used class of pesticides, may be associated with decreased gestational age and lower birth weight. Single nucleotide polymorphisms in paroxanase (PON1) enzyme genotypes may modify the relationships between OP exposure and perinatal outcomes. OBJECTIVE We examined the relationship of prenatal OP insecticide exposure, m...

Journal: :Occupational and environmental medicine 2003
J M Wright J Schwartz D W Dockery

AIMS To examine the effect of trimester specific and pregnancy average total trihalomethane (TTHM) exposure on infant birth weight, low birth weight, and intrauterine growth retardation in term births, as well as gestational age and preterm delivery in all births. METHODS Cross sectional analysis of 56 513 singleton infants born to residents of Massachusetts during 1990. City specific aggrega...

Journal: :Environmental Health Perspectives 2004
Brenda Eskenazi Kim Harley Asa Bradman Erin Weltzien Nicholas P. Jewell Dana B. Barr Clement E. Furlong Nina T. Holland

Although pesticide use is widespread, little is known about potential adverse health effects of in utero exposure. We investigated the effects of organophosphate pesticide exposure during pregnancy on fetal growth and gestational duration in a cohort of low-income, Latina women living in an agricultural community in the Salinas Valley, California. We measured nonspecific metabolites of organoph...

Journal: :Pediatrics 2014
Yun-Chul Hong Surabhi Shah Kulkarni Youn-Hee Lim Eunjeong Kim Mina Ha Hyesook Park Yangho Kim Bung-Nyun Kim Namsoo Chang Se-Young Oh Young-Ju Kim Chooghee Park Eun-hee Ha

BACKGROUND The effects on postnatal growth of maternal exposure to low levels of lead during pregnancy have not been well established. In addition, information is limited regarding the protective effect of dietary calcium intake during pregnancy against the effect of lead for fetal and postnatal growth. We investigated the relationship between prenatal exposure to lead and growth at birth and 6...

Journal: :International Journal of Developmental Neuroscience 1990

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