نتایج جستجو برای: genetically male

تعداد نتایج: 376850  

2017
Ki-Eun Park Amy V. Kaucher Anne Powell Muhammad Salman Waqas Shelley E.S. Sandmaier Melissa J. Oatley Chi-Hun Park Ahmed Tibary David M. Donovan Le Ann Blomberg Simon G. Lillico C. Bruce A. Whitelaw Alan Mileham Bhanu P. Telugu Jon M. Oatley

Genome editing tools have revolutionized the generation of genetically modified animals including livestock. In particular, the domestic pig is a proven model of human physiology and an agriculturally important species. In this study, we utilized the CRISPR/Cas9 system to edit the NANOS2 gene in pig embryos to generate offspring with mono-allelic and bi-allelic mutations. We found that NANOS2 k...

Journal: :Medical Law International 2021

This article examines the content and scope of European Court Human Rights’s first advisory opinion as regards practice cross-border surrogacy in Europe. While concerns recognition legal parentage an intended mother, this considers whether reasoning could be applied to male couples who avail surrogacy. It is argued that non-genetically related father couple a directly comparable position mother...

Journal: :Reproduction 2014
Kim C Jonas Olayiwola O Oduwole Hellevi Peltoketo Susana B Rulli Ilpo T Huhtaniemi

The advent of technologies to genetically manipulate the mouse genome has revolutionised research approaches, providing a unique platform to study the causality of reproductive disorders in vivo. With the relative ease of generating genetically modified (GM) mouse models, the last two decades have yielded multiple loss-of-function and gain-of-function mutation mouse models to explore the role o...

Journal: :Science 2004
Julia C Jones Mary R Myerscough Sonia Graham Benjamin P Oldroyd

A honey bee colony is characterized by high genetic diversity among its workers, generated by high levels of multiple mating by its queen. Few clear benefits of this genetic diversity are known. Here we show that brood nest temperatures in genetically diverse colonies (i.e., those sired by several males) tend to be more stable than in genetically uniform ones (i.e., those sired by one male). On...

Journal: :Genetics 2001
M Fujisawa K Hayashi T Nishio T Bando S Okada K T Yamato H Fukuzawa K Ohyama

The liverwort Marchantia polymorpha has X and Y chromosomes in the respective female and male haploids. Here we report the successful exploitation of representational difference analyses to isolate DNA markers for the sex chromosomes. Two female-specific and six male-specific DNA fragments were genetically confirmed to originate from the X and Y chromosomes, respectively.

Journal: :Historia, ciencias, saude--Manguinhos 2009
Maria Clara Coelho Camara Carmem L C Marinho Maria Cristina Rodrigues Guilam Rubens Onofre Nodari

Based on a bibliographic review, the article identifies and offers a critical analysis of scientific production by the public health field in Brazil on genetically modified organisms and food (in)security. Of the 716 articles found on the portals of the Scientific Electronic Library Online (SciELO) and the Coordinating Agency for the Development of Higher Education (Capes), only 8 address the f...

Journal: :Imaging 2022

Abstract Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a hereditary vascular disorder inherited in an autosomal dominant manner. MRI plays crucial role the diagnosis follow-up of patients. Characteristic lesions include symmetric bilateral white matter periventricular hyperintensities, lacunar infarcts cerebral microbleeds. In our case r...

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