genetic polymorphisms

uterine leiomyoma (ul) is the most common benign smooth muscle cell tumor with as yet unknown etiology and pathogenesis. this study was carried out to investigate the association of esr1-351 a>g, esr1 -397 t>c and cyp1a1 (ile462val) polymorphisms with ul in female patients of iranian origin. in this case-control study, 276 patients with ul and 156 healthy women were recruited. the genetic polym...

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association between twenty five gens with stroke subtypes in a persian population, a database structure

Journal: :genetics in the 3rd millennium 0

ariane sadr-nabavi

stroke is the third cause of death in the world after the cancer and cardiovascular disease. . it has been shown that stroke in northeast of iran occurs approximately one decade earlier than in western countries. reasons for the high stroke incidence among persian are not yet clear. it is the first gene-association study in persian population, which determines the relationship between 25 gene v...

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Associations of common polymorphisms in GCKR with metabolic syndrome

Journal: مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران 2018

Asiyeh Sadat Zahedi, Bahareh Sedaghati-Khayat, Fereidoun Azizi, Maryam Sadat Daneshpour, Sara Behnami,

Background: Metabolic syndrome (MetS) is characterized by a combination of cardio-metabolic risk factors. Given that genetic factors have been shown to contribute to individual susceptibility to MetS, the identification of genetic markers for disease risk is essential. Recent studies revealed that rs780094 and rs1260326 of glucokinase regulatory gene (GCKR) are associated with serum triglycerid...

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