the improvement of high-through-put gene profiling based microarrays technology has provided monitoring the expression value of thousands of genes simultaneously. detailed examination of changes in expression levels of genes can help physicians to have effi cient diagnosing, classification of tumors and cancer’s types as well as effective treatments. finding genes that can classify the group of...

Aim 3,4-methylenedioxymethamphetamine (MDMA) is one of the most widespread illegal drugs, used particularly by young people in the 15-34 age group. MicroRNAs (miRNAs) are endogenously synthesized, non-coding and small RNAs that post-transcriptionally regulate their target genes’ expression by inhibiting protein translation or degradation. miRNAs are increasingly implicated in drug-related...

Yeast cells were induced to proliferate peroxisomes, and microarray transcriptional profiling was used to identify PEX genes encoding peroxins involved in peroxisome assembly and genes involved in peroxisome function. Clustering algorithms identified 224 genes with expression profiles similar to those of genes encoding peroxisomal proteins and genes involved in peroxisome biogenesis. Several pr...

Gene expression microarrays are the most widely used technique for genome-wide expression profiling. However, microarrays do not perform well on formalin fixed paraffin embedded tissue (FFPET). Consequently, microarrays cannot be effectively utilized to perform gene expression profiling on the vast majority of archival tumor samples. To address this limitation of gene expression microarrays, we...

Functional links between genes can be predicted using phylogenetic profiling, by correlating the appearance and loss of homologs in subsets of species. However, effective genome-wide phylogenetic profiling has been hindered by the large fraction of human genes related to each other through historical duplication events. Here, we overcame this challenge by automatically profiling over 30,000 gro...

Most simulations of biological evolu tion depend on a rather restricted set of properties In this paper a richer model based on di erential gene expres sion is introduced to control develop mental processes in an arti cial evolu tionary system Di erential gene expres sion is used to get di erent cell types and to modulate cell division and cell death One of the advantages using developmental pr...

In addition to controlled expression of genes by specific regulatory circuits, the abundance proteins and transcripts can also be influenced physiological states cell such as growth rate metabolism. Here we examine control gene metabolism, analyzing a multi-omics dataset consisting absolute-quantitative abundances transcriptome, proteome, amino acids in 22 steady-state yeast cultures. We find t...

Biaya operasional merupakan keseluruhan biaya-biaya komersial yang dikeluarkan untuk menunjang atau mendukung kegiatan aktifitas perusahaan mencapai sasaran telah ditentukan,yang terdiri beban penjualan serta biaya administrasi dan umum, laba bersih adalah selisih bersih,semua pendapatan keuntungan terhadap kerugian.Objek Penelitia CV.Junior Expres Medan dengan Sampel sebayak 5 Tahun data Keuan...