The aim of the present study is to evaluate the validity of the simplified reference tissue model (SRTM) and of Logan graphical analysis with reference tissue (LGAR) for quantification of histamine H1 receptors (H1Rs) by using positron emission tomography (PET) with [11C]doxepin. These model-based analytic methods (SRTM and LGAR) are compared to Logan graphical analysis (LGA) and to the one-tis...

The high-affinity radioligand [(18)F]fallypride (FP) is frequently used for quantification of striatal/extrastriatal D(2/3) receptors and the receptor occupancies of antipsychotics (APs). Its 110 minutes half-life allows long scan durations. However, the optimum scan duration is a matter of debate. This investigation focuses on scan-duration-related effects on simplified reference tissue model ...

In February 2000 the first mission using space-borne single-pass-interferometry was launched – the Shuttle Radar Topography Mission (SRTM). The goal of the mission was to survey the Earth surface and to generate a homogeneous elevation data set of the world with a grid spacing of 1 arcsec. Antennas with two different wavelengths were used: Beside the American SIR-C the German / Italian X-SAR sy...

The 1:50.000 topographic maps present a nominal horizontal accuracy of 20 meters and a nominal vertical accuracy of 10 meters with 90% confidence. The data were in most cases extracted with photogrammetric techniques from aerial stereo-photographs during the 80’s. The usual update rate for these maps ranges from ten to twenty years. The Advanced Spaceborn Thermal Emission and Reflection Radiome...

In this research, Interferometric Synthetic Aperture Radar (IFSAR) and Shuttle Radar Topography Mission (SRTM) data are used to delineate a portion of the Saint Louis Bay watershed (Mississippi). In addition to these two digital elevation databases, the National Elevation Data (NED) and the United States Geological Service’ Digital Elevation Model (USGS-DEM) are also used for delineation. Resul...

We present one of the first studies in which interferometric synthetic aperture radar (InSAR) data from the Shuttle Radar Topography Mission (SRTM) are analyzed with regard to the detectability of ocean surface current variations. The InSAR system of SRTM was designed for high-resolution topographic mapping, using two SAR antennas on a Space Shuttle with a cross-track separation of 60 m. For te...

Our goal was to identify suitable image quantification methods to image 5-hydroxytryptamine2A (5-HT2A) receptors in vivo in Mdr1a knockout (KO) rats (i.e., P-glycoprotein KO) using 123I-R91150 single-photon emission computed tomography (SPECT). The 123I-R91150 binding parameters estimated with different reference tissue models (simplified reference tissue model [SRTM], Logan reference tissue mo...

The main objective of this work is to design an automatic image processing tool for lineament mapping from LANDSAT-TM satellite data. In doing so, three procedures are involved: (i) image enhancement using histogram equalization technique; (ii) automatic lineament detection using Canny algorithm; and (iii) three-dimensional (3D) lineament visualization using SRTM data. The study shows that Cann...

For an extension of the water catchments areas for the Greater Istanbul Municipality investigations in a mountainous forest area in Turkey, at the Bulgarian border, named Istiranca, have been made. In the project area a height model from SPOT-5 HRS, the SRTM C-band height model and a digital elevation model (DEM) for the topographic map 1:25 000 are available like also a Cartosat-1 stereo pair....

A DEM is one of the most useful information for spatial modelling and monitoring. Several DEMs have been published in the public domain like SRTM and ASTER GDEM with and without considering the horizontal and vertical misallocation of single input data. Results of that are for example the inherent errors in the ASTER GDEM V1 dataset as well as the known striping in the SRTM dataset. Therefore, ...