During the last few decades, pharmaceutical industry gave more importance to controlled release of dosage forms like solid formulation, semi and topicalpreparation dueto efficacy patient compliance. Normal topical preparations have some disadvantages unpleasant odour, greasiness, skin irritation reported in study cases. Also many topicalpreparations fail reach systemic circulation sufficient am...

Abstract Background A microsponge delivery system (MDS) is an innovative and unique way of delivering drugs in a structured manner. Using drug delivery, regulated may now be achieved quickly easily. Main body MDS comprises porous microspheres ranging size from 5 to 300 microns, with large structure very tiny spherical shape. normally used deliver via topical channels, but they have recently sho...

Context: Drugs that are easily absorbed from the gastrointestinal tract (GIT) and have a short halflife are eliminated quickly from the blood circulation, require frequent dosing. To avoid this, the oral controlled release (CR) formulations have been developed in an attempt to release the drug slowly into the GIT and maintain a constant drug concentration in the serum for longer period of time....

Objective: The objective of the present study was to compare release effect Luliconazole from different polymeric (Hydrophilic and Hydrophobic) microsponges prepared using varying concentrations. best microsponge selected incorporated into gel (Natural synthetic) drug is determined compared with marketed formulation.
 Methods: Polymers such as EC, HPMC, Eudragit RSPO PVA emulsifier, solven...