BACKGROUND Although many studies have found an association between Helicobacter pylori infection and the development of gastric cancer, many aspects of this relation remain uncertain. METHODS We prospectively studied 1526 Japanese patients who had duodenal ulcers, gastric ulcers, gastric hyperplasia, or nonulcer dyspepsia at the time of enrollment; 1246 had H. pylori infection and 280 did not...

Unilateral vagotomy causes atrophy of the denervated fundic mucosa in rat stomachs. We examined whether or not unilateral vagotomy delays healing of gastric ulcers induced on the denervated mucosa. Kissing ulcers were induced in the fundus of rat stomachs by intraluminal application of an acetic acid solution. Anterior unilateral vagotomy was performed subdiaphragmatically at the time of ulcera...

AIMS To determine the gastric distribution of Helicobacter pylori in patients with duodenal and gastric ulcers; and to examine the mucosal inflammatory response. METHODS Patients with newly diagnosed, uncomplicated duodenal and gastric ulcers were endoscoped and two biopsy specimens each taken from the antrum and the body. Specimens were evaluated blind by one pathologist to determine H pylor...

The present investigation was undertaken, to study the gastro-protective potential of aripiprazole (ARI) an atypical antipsychotic drug in ethanol induced gastric ulcers in rats. ARI (10, 30, 100 mg/kg) was tested for gastric secretion and antiulcer activity in different groups of male Sprague Dawley rats. Gastric secretion and acidity studies were performed in pylorus ligated rats while indice...

Eighteen mature, healthy horses were divided into three groups (six per group) receiving either no treatment, 15 consecutive days of phenylbutazone (PBZ), or 15 consecutive days of suxibuzone (SBZ) at recommended label doses. Horses underwent endoscopy before and after the treatment period and were assigned gastric ulcer scores. Gastric ulcer number and severity scores were similar across treat...

persian oak (quercus brantii lindl., the fagaceae family) is a medicinal plant which seed flour is used to treat inflammatory and gastric ulcers by the tribes in southwestern iran. the current study was done to evaluate the effect of hydro-alcoholic extract of q. brantii seed flour for treatment of gastric ulcers induced by ethanol in wistar rats. the hydro-alcoholic extract of q. brantii was t...

background: data suggest that v. arctostaphylos, b. thunbergii var. atropurpurea, e. angustifolia and l. acanthodes may prevent gastric ulcers induced by non-steroidal anti-inflammatory drugs (nsaids). objective: to explore the ulcer-protective potential of these plants in indomethacin-induced gastric ulcers in rats. methods: saline, hydro-alcoholic extract of each plant (100, 400, 800 mg/kg) a...

Acute ulcers of the gastric mucosa are found in a large percentage of dogs and cats dying after adrenalectomy. These ulcers seem to develop during the moribund period. They are apparently peptic ulcers forming at the site of local hemorrhages in the gastric mucosa. They are true acute ulcers, usually penetrating to the muscularis mucosa with a total loss of epithelium. They develop in the absen...

JT OR MANY YEARS it has been the opinion of many physicians, physiologists, and psychologists that nervous stimuli brought about by worrying, anxiety, fear, and conflict can lead to gastrointestinal changes which may result in the formation of gastric ulcers. However, no one has ever shown experimentally that such emotional factors actually lead to the formation of gastric ulcers. That it is no...

An ulcer in the stomach is a common digestive system ailment. Gastric ulcers are more likely to develop if one drinks alcohol regularly. Despite extensive availability of treatment options, there just few preventative regimes. In animal trials, herbal remedies have been found prevent formation ethanol-induced ulcers. Histamine receptor 2 antagonists similar or higher ability inhibit treatments....