نتایج جستجو برای: gambogic acid
تعداد نتایج: 747447 فیلتر نتایج به سال:
Eleven known caged polyprenylated xanthones 1-11 were isolated from the resin of Garcinia hanburyi Hook. f., and their structures were identified by their MS, NMR and UV spectra. These xanthones showed significant cytotoxicities against four human cancer cell lines (HeLa, A549, HCT-116, and HepG-2) and strong inhibition against the proliferation of the HUVEC cell line in vitro by the MTT method...
Received: Revised: Accepted: Published online: March 26, 2015 July 23, 2015 August 25, 2015 December 31, 2015 Tibial Dyschondroplasia (TD) is an important leg problem in fast growing birds that disturbs the proximal tibial growth plate. A study was conducted to evaluate the effects of gambogic acid (GA) on hsp-90 expressions and antioxidant capability in thiram-induced TD chicken. One hundred a...
Gambogic acid (GA) is in a phase II clinical trial as an antitumor and antiangiogenesis agent. In this study, 36 GA derivatives were synthesized and screened in a zebrafish model to evaluate their antiangiogenic activity and toxicity. Derivatives 4, 32, 35, 36 effectively suppressed the formation of newly grown blood vessels and showed lower toxicities than GA as evaluated by zebrafish heart ra...
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