Given the rise of bacterial resistance against antibiotics, we urgently need alternative strategies to fight infections. Some propose we should disarm rather than kill bacteria, through targeted disruption of their virulence factors. It is assumed that this approach (i) induces weak selection for resistance because it should only minimally impact bacterial fitness, and (ii) is specific, only in...

Salmonella enterica is a foodborne zoonotic pathogen of significant public health concern. We have characterized the virulence and antimicrobial resistance gene content of 95 Salmonella isolates from 11 serovars by DNA microarray recovered from UK livestock or imported meat. Genes encoding resistance to sulphonamides (sul1, sul2), tetracycline [tet(A), tet(B)], streptomycin (strA, strB), aminog...

Il saggio colloca il film 18 regali di Francesco Amato all’interno della tradizione del fantastico. Particolare rilievo è dato allo studio relazione fra individuo e scienza, agli oggetti mediatori alla rappresentazione corpo umano. L’autore propone l’interpretazione come una galleria immagini che ricevono l’eredità dei topoi tipici fantastico cinematografico letterario.

the development times and the survival rates of different stages of habrobracon hebetor say reared on the last instar larvae of galleria mellonella (l.) were compared at ten different constant temperatures (16 - 38 âºc). the development time of immature stages of the parasitoid, h. hebetor, decreased as the temperature increased in the range of 16 to 38 âºc. however, no larvae could survive and...

Galleria mellonella larvae are widely used for assessing the virulence of microbial pathogens and for measuring the in vivo activity of antimicrobial agents and produce results comparable to those that can be obtained using mammals. The aim of the work described here was to ascertain the effect of pre-incubation at 15°C for 1, 3, 6 or 10 weeks on the susceptibility of larvae to infection with C...

an entomopathogenic nematode was isolated by galleria baiting technique from soil samples collected near marand, east azarbaijan province, north-west of iran during 2003. based on morphological and morphometric characters, as well as molecular data it was identified as steinernema bicornutum tallosi, peters & ehlers, 1995. morphometrics comparison of the isolate with the type species showed no ...

The work describes purification and biochemical characterization of two inducible antimicrobial peptides from the hemolymph of Galleria mellonella. The peptides were isolated by a sequence of reversed-phase chromatography steps from the hemolymph of larvae immunized with viable bacteria. The first peptide is a member of the cecropin family while the second one is rich in proline residues and ha...

The study of bacterial virulence often requires a suitable animal model. Mammalian models of infection are costly and may raise ethical issues. The use of insects as infection models provides a valuable alternative. Compared to other non-vertebrate model hosts such as nematodes, insects have a relatively advanced system of antimicrobial defenses and are thus more likely to produce information r...